Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11701259 | 0.87 | KMT2A (0.44) | RAB9ANPC1POLBHPGDSMN1; SMN2 | |
| SCHEMBL11694491 | 0.80 | AKR1B1 (0.46) | RAB9APOLBHPGDTDP1ALDH1A1 | |
| SCHEMBL11694521 | 0.77 | FFAR1 (0.43) | — | |
| SCHEMBL4557726 | 0.76 | PPID (0.40) | RAB9ANPC1POLBHPGDSMN1; SMN2 | |
| SCHEMBL3620383 | 0.76 | RAB9A (0.70) | RAB9ANPC1POLBHPGDSMN1; SMN2 | |
| SCHEMBL11696212 | 0.75 | CYP4F2 (0.38) | RAB9ANPC1CYP2D6 | |
| SCHEMBL11693436 | 0.75 | GSK3B (0.38) | RAB9ANPC1POLBHPGDSMN1; SMN2 | |
| SCHEMBL11696376 | 0.74 | SMN1; SMN2 (0.46) | RAB9ANPC1POLBHPGDSMN1; SMN2 | |
| SCHEMBL2937839 | 0.73 | ALDH1A1 (0.65) | RAB9ANPC1HPGDSMN1; SMN2TDP1 | |
| SCHEMBL2937877 | 0.73 | SMN1; SMN2 (0.70) | RAB9ANPC1HPGDSMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6967196-B1 | Sulfonamide compounds and uses thereof | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-11-22 | — | — | US | disclosed |