SCHEMBL640076

SCHEMBL640076

CCN(CC)C(=O)[O-].CCN(CC)C(=O)[O-].[Ni+2]

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.43
MMP1 P03956 1/20 0.42
MMP2 P08253 1/20 0.42
MMP3 P08254 1/20 0.42
MMP8 P22894 1/20 0.42
FFAR3 O14843 2/20 0.36
HDAC3 O15379 2/20 0.36
HDAC1 Q13547 2/20 0.36
HDAC2 Q92769 2/20 0.36
HDAC8 Q9BY41 2/20 0.36
CA1 P00915 4/20 0.36
CA12 O43570 3/20 0.36
CA9 Q16790 3/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
EHMT2 Q96KQ7 3/20 0.35
EHMT1 Q9H9B1 3/20 0.35
ABCB11 O95342 2/20 0.35
HTT P42858 2/20 0.35
GSDMD P57764 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7639287 0.94 LMNA (0.43) LMNAMMP1MMP2MMP3MMP8
SCHEMBL7008575 0.94 LMNA (0.43) LMNAMMP1MMP2MMP3MMP8
SCHEMBL674788 0.94 LMNA (0.43) LMNAMMP1MMP2MMP3MMP8
Silver SCHEMBL7155501 0.94
SCHEMBL7155783 0.94 LMNA (0.43) LMNAMMP1MMP2MMP3MMP8
SCHEMBL150701 0.94 LMNA (0.43) LMNAMMP1MMP2MMP3MMP8
SCHEMBL7645015 0.94 LMNA (0.43) LMNAMMP1MMP2MMP3MMP8
SCHEMBL672335 0.94 LMNA (0.43) LMNAMMP1MMP2MMP3MMP8
SCHEMBL8623661 0.94 LMNA (0.43) LMNAMMP1MMP2MMP3MMP8
SCHEMBL28491917 0.94 LMNA (0.43) LMNAMMP1MMP2MMP3MMP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030027935-A1 Acrylic rubber composition, crosslinkable acrylic rubber composition, and crosslinked object obtained therefrom ZEON CORPORATION (JP) 2003-02-06 US claimed
EP-1270666-A1 ACRYLIC RUBBER COMPOSITION, CROSSLINKABLE ACRYLIC RUBBER COMPOSITION, AND CROSSLINKED OBJECT OBTAINED THEREFROM Zeon Corporation (JP) 2003-01-02 EP claimed
EP-3969490-B1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND TIRE COMPONENTS BRIDGESTONE CORP (JP) 2026-03-25 EP disclosed
US-20250389555-A1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-12-25 US disclosed
US-12410263-B2 Modified high-Cis polybutadiene polymer, related methods and rubber compositions BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-09-09 US disclosed
US-12264232-B2 Modified high-cis polybutadiene polymer, related methods and tire components BRIDGESTONE CORPORATION (JP) 2025-04-01 US disclosed
US-20250066516-A1 HYDROGENATED POLYBUTADIENE POLYMERS AND RUBBER COMPOSITIONS INCORPORATING SAME BRIDGESTONE CORPORATION (JP) 2025-02-27 US disclosed
CN-113825777-B Modified high cis polybutadiene polymers, related methods and tire components 株式会社普利司通 2025-01-28 CN disclosed
EP-4495146-A2 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS Bridgestone Americas Tire Operations, LLC (US) 2025-01-22 EP disclosed
EP-4457250-A1 HYDROGENATED POLYBUTADIENE POLYMERS AND RUBBER COMPOSITIONS INCORPORATING SAME Bridgestone Corporation (JP) 2024-11-06 EP disclosed
EP-3966259-B1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS BRIDGESTONE AMERICAS TIRE OPERATIONS LLC (US) 2024-10-30 EP disclosed
US-20080255327-A1 addition polymerization of conjugated polyene monomer in the presence of polymerization catalysts comprising a mixture of a nickel-containing compound, an alkylating agent, a fluorine-containing compound, a carboxylic acid and an alcohol; controlling gelation, branching and molecular weight; efficiency BRIDGESTONE CORPORATION (JP) 2008-10-16 US disclosed
WO-2008045372-A2 BRANCHED POLYMERS AND METHODS FOR THEIR SYNTHESIS AND USE BRIDGESTONE CORPORATION (JP) 2008-04-17 WO disclosed
US-20070117942-A1 Nickel-based catalyst composition BRIDGESTONE CORPORATION 2007-05-24 US disclosed
EP-1788003-A1 Nickel-based catalyst composition Bridgestone Corporation (JP) 2007-05-23 EP disclosed
US-6699813-B2 COMPOSITION THAT IS COMBINATION OF OR REACTION PRODUCT OF LANTHANIDE COMPOUND, ALKYLATING AGENT, NICKEL-CONTAINING COMPOUND, AND OPTIONALLY HALOGEN-CONTAINING COMPOUND THAT INCLUDES ONE OR MORE LABILE HALOGEN ATOMS BRIDGESTONE CORPORATION (JP) 2004-03-02 US disclosed
US-20030176276-A1 Lanthanide-based catalyst composition for the manufacture of polydienes BRIDGESTONE CORPORATION (JP) 2003-09-18 US disclosed
US-20030027935-A1 Acrylic rubber composition, crosslinkable acrylic rubber composition, and crosslinked object obtained therefrom ZEON CORPORATION (JP) 2003-02-06 US disclosed
EP-1270666-A1 ACRYLIC RUBBER COMPOSITION, CROSSLINKABLE ACRYLIC RUBBER COMPOSITION, AND CROSSLINKED OBJECT OBTAINED THEREFROM Zeon Corporation (JP) 2003-01-02 EP disclosed
JP-2000302917-A RUBBER COMPOSITION AND CROSS-LINKED MATERIAL NIPPON ZEON CO LTD 2000-10-31 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250389555-A1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS MALT1, INO80C, RTCB LMNA 450/4885MMP1 4061/4885MMP2 4750/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.