Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 4/20 | 0.36 |
| ▸ | CA12 | O43570 | 3/20 | 0.36 |
| ▸ | CA9 | Q16790 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | EHMT2 | Q96KQ7 | 3/20 | 0.35 |
| ▸ | EHMT1 | Q9H9B1 | 3/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | GSDMD | P57764 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL640076 | 0.94 | LMNA (0.43) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL150701 | 0.94 | LMNA (0.43) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL7639287 | 0.94 | LMNA (0.43) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL8623661 | 0.94 | LMNA (0.43) | LMNAMMP1MMP2MMP3MMP8 | |
| Silver SCHEMBL7155501 | 0.94 | — | — | |
| SCHEMBL7008575 | 0.94 | LMNA (0.43) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL674788 | 0.94 | LMNA (0.43) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL7155783 | 0.94 | LMNA (0.43) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL672335 | 0.94 | LMNA (0.43) | LMNAMMP1MMP2MMP3MMP8 | |
| SCHEMBL28495513 | 0.94 | LMNA (0.43) | LMNAMMP1MMP2MMP3MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355748-B1 | ADDITION POLYMERIZATION USING GROUP IV METAL SPIROCYCLE COMPLEX AS CATALYST AND ACTIVATING COCATALYST | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION | 2002-03-12 | — | — | US | disclosed |
| US-6326445-B1 | REACTION PRODUCT CONTAINING FULVENE COMPOUND | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION | 2001-12-04 | — | — | US | disclosed |
| US-6100212-A | A SELF-ASSEMBLED, SINGLE-SITE METALLOCENE CATALYST THAT IS EASILY AND COST EFFECTIVELY MADE FROM A SPIROCYCLE, E.G. SPIRO(2.4)HEPTANE, A GROUP 4 METAL, A LIGAND, AN ANIONIC GROUP AND AN ACTIVATING COCATALYST; NO CATALYST ISOLATION NECESSARY | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2000-08-08 | — | — | US | disclosed |
| US-6054405-A | CONTAINING A FLUVENE COMPOUND | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 2000-04-25 | — | — | US | disclosed |
| EP-0927728-A1 | Catalyst composition for the polymerization of olefins | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1999-07-07 | — | — | EP | disclosed |