SCHEMBL6401400

SCHEMBL6401400

COc1ccc(P(c2ccc(OC)cc2)c2cccc3ccccc23)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.49
KMT2A Q03164 4/20 0.43
NPC1 O15118 2/20 0.43
TDP1 Q9NUW8 2/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
MAPT P10636 3/20 0.42
TUBB4A P04350 2/20 0.42
TUBB P07437 2/20 0.42
TUBA3C P0DPH7 2/20 0.42
TUBA1B P68363 2/20 0.42
TUBA4A P68366 2/20 0.42
TUBB4B P68371 2/20 0.42
TUBB3 Q13509 2/20 0.42
TUBB2A Q13885 2/20 0.42
TUBB8 Q3ZCM7 2/20 0.42
TUBA3E Q6PEY2 2/20 0.42
TUBA1A Q71U36 2/20 0.42
TUBA1C Q9BQE3 2/20 0.42
TUBB6 Q9BUF5 2/20 0.42
TUBB2B Q9BVA1 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7058634 0.97 RAB9A (0.46) RAB9AKMT2ANPC1TDP1L3MBTL1
SCHEMBL301026 0.83 MAPT (0.51) RAB9AKMT2ANPC1TDP1L3MBTL1
SCHEMBL1988632 0.83 CA1 (0.50) RAB9ANPC1TDP1L3MBTL1MAPT
SCHEMBL15658738 0.81 ALDH1A1 (0.43) TDP1L3MBTL1CYP1A2CYP2A6ALDH1A1
SCHEMBL7795643 0.81 MAPT (0.45) RAB9AKMT2ANPC1TDP1L3MBTL1
SCHEMBL6680057 0.80 CYP2A6 (0.43) RAB9AKMT2ANPC1TDP1L3MBTL1
SCHEMBL132132 0.79 CYP3A4 (0.48) TDP1CYP1A2CYP2A6ALDH1A1KEAP1
SCHEMBL7569519 0.79 CYP3A4 (0.48) TDP1CYP1A2CYP2A6ALDH1A1KEAP1
SCHEMBL30170447 0.79 CYP3A4 (0.48) TDP1CYP1A2CYP2A6ALDH1A1KEAP1
SCHEMBL971061 0.79 CYP1A2 (0.39) RAB9AKMT2ANPC1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6955851-B2 Hydroxyaryl phosphine oxides, glycidyl ethers and epoxy compositions, composites and laminates derived therefrom PABU SERVICES, INC. (US) 2005-10-18 US disclosed
US-6733698-B2 Mixture of mono-, bis- and tris-(hydroxyaryl) phosphine oxides useful to make polyglycidyl ethers or in epoxy compositions PABU SERVICES, INC. 2004-05-11 US disclosed