Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 8/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21969530 | 0.75 | PDE3B (0.63) | MAPTNPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL21858396 | 0.75 | KMT2A (0.74) | MAPTNPC1RAB9AKMT2AATM | |
| SCHEMBL31206271 | 0.75 | KMT2A (0.74) | MAPTNPC1RAB9AKMT2AATM | |
| SCHEMBL10413428 | 0.75 | PDE3B (0.48) | MAPTNPC1RAB9AKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL1143011 | 0.74 | ACHE (0.72) | KDRMAPTNPC1RAB9AKMT2A | |
| SCHEMBL6405008 | 0.72 | MAOB (0.45) | KDRMAPTKMT2AMEN1MAOB | |
| SCHEMBL10472821 | 0.72 | JAK2 (0.53) | MAPTNPC1RAB9AKMT2AATM | |
| SCHEMBL12870270 | 0.72 | MAPT (0.53) | KDRMAPTNPC1RAB9AKMT2A | |
| SCHEMBL13568487 | 0.71 | MAPT (0.53) | KDRMAPTNPC1RAB9AKMT2A | |
| SCHEMBL6199415 | 0.70 | HTR2A (0.64) | KDRMAPTNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050059658-A1 | Pyridazinone | BAYER AKTIENGESELLSCHAFT (DE) | 2005-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050059658-A1 | Pyridazinone | TYMP, TPMT, PDXK | KDR 2962/4885MAPT 2679/4885NPC1 3414/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.