Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11424155 | 1.00 | LMNA (0.42) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL122818 | 1.00 | LMNA (0.42) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL319408 | 0.94 | LMNA (0.46) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL3073599 | 0.94 | LMNA (0.46) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL2635052 | 0.94 | LMNA (0.46) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL517269 | 0.94 | LMNA (0.46) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| Hydrochloric Acid SCHEMBL8587068 | 0.92 | LMNA (0.44) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL10534255 | 0.88 | LMNA (0.41) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| Phosphoric Acid SCHEMBL5789520 | 0.87 | LMNA (0.39) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| Acetic Acid SCHEMBL7951061 | 0.87 | USP2 (0.44) | LMNAL3MBTL1TDP1USP2SLCO1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8119364-B2 | Methods for generating analogs of coenzyme A | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-02-21 | — | — | US | disclosed |
| US-20100304430-A1 | Methods for Generating Analogs of Coenzyme A | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-12-02 | — | — | US | disclosed |
| US-7727738-B2 | Methods for generating analogs of coenzyme A | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-06-01 | — | — | US | disclosed |
| US-20070128683-A1 | Metabolic delivery of coenzyme A analogs | NATIONAL SCIENCE FOUNDATION | 2007-06-07 | — | — | US | disclosed |