SCHEMBL122818

SCHEMBL122818

NO[C@H](C=O)[C@H](O)[C@H](O)CO

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
TDP1 Q9NUW8 1/20 0.40
USP2 O75604 1/20 0.38
SLCO1B1 Q9Y6L6 1/20 0.38
AKR1B1 P15121 1/20 0.37
PDE4A P27815 1/20 0.35
KDM4E B2RXH2 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11424155 1.00 LMNA (0.42) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL640184 1.00 LMNA (0.42) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL319408 0.94 LMNA (0.46) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL3073599 0.94 LMNA (0.46) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL2635052 0.94 LMNA (0.46) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL517269 0.94 LMNA (0.46) LMNAL3MBTL1TDP1USP2SLCO1B1
Hydrochloric Acid SCHEMBL8587068 0.92 LMNA (0.44) LMNAL3MBTL1TDP1USP2SLCO1B1
SCHEMBL10534255 0.88 LMNA (0.41) LMNAL3MBTL1TDP1USP2SLCO1B1
Phosphoric Acid SCHEMBL5789520 0.87 LMNA (0.39) LMNAL3MBTL1TDP1USP2SLCO1B1
Acetic Acid SCHEMBL7951061 0.87 USP2 (0.44) LMNAL3MBTL1TDP1USP2SLCO1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 234 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018106546-A1 METHODS OF DETECTION OF ANTIBIOTIC-RESISTANT BACTERIA SILVER LAKE RESEARCH CORPORATION (US) 2018-06-14 WO claimed
US-20180156796-A1 Methods of Detection of Antibiotic-Resistant Bacteria SILVER LAKE RESEARCH CORPORATION (US) 2018-06-07 US claimed
US-20260115279-A1 Methods for Isolation of Lipid-Disc Compositions and Uses Thereof VIB VZW (BE) 2026-04-30 US disclosed
US-12593839-B2 Fabric care composition comprising a mixture of cationic biocide, functionalized alkylpoyglycoside, and sulfolaurate salt BROADOUS SR TIMOTHY (US) 2026-04-07 US disclosed
US-12544435-B2 Neisserial surface protein a (NSPA) variants and methods of use thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-02-10 US disclosed
WO-2025264672-A1 INHIBITORS OF MOBILIZED COLISTIN RESISTANCE ENZYME (MCR-1) AND METHODS OF USE THEREOF BAYLOR COLLEGE OF MEDICINE (US) 2025-12-26 WO disclosed
EP-4658292-A1 PRODUCTS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF PSEUDOMONAS INFECTIONS The Administrators of The Tulane Educational Fund (US) 2025-12-10 EP disclosed
WO-2024163916-A9 PRODUCTS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF PSEUDOMONAS INFECTIONS THE ADMINISTRATORS OF THE TULANE EDUCATIONAL FUND (US) 2025-07-17 WO disclosed
US-20250154206-A1 Factor H Binding Protein Variants and Methods of Use Thereof CHILDREN'S HOSPITAL & RESEARCH CENTER AT OAKLAND 2025-05-15 US disclosed
US-12295965-B2 Methods of treating sepsis using anti-sepsis lipid a (ASLA) based therapeutics UNIVERSITY OF MARYLAND, BALTIMORE (US) 2025-05-13 US disclosed
US-20250136648-A1 Factor H Binding Protein Variants and Methods of Use Thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-05-01 US disclosed
EP-0536302-A1 IMPROVED ADJUVANTS AND VACCINES. UNIV EMORY (US) 1993-04-14 EP disclosed
EP-0466838-A1 NOVEL LIPID A DERIVATIVES AND USES THEREFOR WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1992-01-22 EP disclosed
WO-1992000101-A1 IMPROVED ADJUVANTS AND VACCINES EMORY UNIVERSITY (US) 1992-01-09 WO disclosed
US-5041427-A Protection Against Gramnegative Endotoxin WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1991-08-20 US disclosed
WO-1991001134-A1 NOVEL LIPID A DERIVATIVES AND USES THEREFOR WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1991-02-07 WO disclosed
EP-0143840-B1 MONOSACCHARIDE COMPOUNDS HAVING IMMUNOSTIMULATING ACTIVITY WISCONSIN ALUMNI RESEARCH FOUNDATION (US) 1990-08-29 EP disclosed
EP-0143840-A4 MONOSACCHARIDE COMPOUNDS HAVING IMMUNOSTIMULATING ACTIVITY. WISCONSIN ALUMNI RES FOUND (US) 1986-02-13 EP disclosed
EP-0143840-A1 MONOSACCHARIDE COMPOUNDS HAVING IMMUNOSTIMULATING ACTIVITY. WISCONSIN ALUMNI RES FOUND (US) 1985-06-12 EP disclosed
WO-1984004526-A1 MONOSACCHARIDE COMPOUNDS HAVING IMMUNOSTIMULATING ACTIVITY WISCONSIN ALUMNI RES FOUND (US) 1984-11-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12295965-B2 Methods of treating sepsis using anti-sepsis lipid a (ASLA) based therapeutics S1PR1, ASS1, S1PR3 LMNA 1773/4885L3MBTL1 1055/4885TDP1 3384/4885
US-12593839-B2 Fabric care composition comprising a mixture of cationic biocide, functionalized alkylpoyglycoside, and sulfolaurate salt CUTA, MGAM, PLOD3 LMNA 857/4885L3MBTL1 885/4885TDP1 1372/4885
US-20260115279-A1 Methods for Isolation of Lipid-Disc Compositions and Uses Thereof STT3B, DDOST, PLTP LMNA 989/4885L3MBTL1 851/4885TDP1 2178/4885
US-12544435-B2 Neisserial surface protein a (NSPA) variants and methods of use thereof CFH, ASNS, PSPH LMNA 797/4885L3MBTL1 1281/4885TDP1 783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.