SCHEMBL6401908

SCHEMBL6401908

O=C(Cc1ccc(Oc2ccc3cc(O)ccc3c2)cc1)Nc1ccccc1C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 8/20 0.67
KMT2A Q03164 4/20 0.57
MEN1 O00255 3/20 0.57
CASP3 P42574 1/20 0.57
SENP8 Q96LD8 1/20 0.57
SENP7 Q9BQF6 1/20 0.57
SENP6 Q9GZR1 1/20 0.57
ALDH1A1 P00352 5/20 0.53
KDM4E B2RXH2 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
L3MBTL1 Q9Y468 2/20 0.53
LMNA P02545 1/20 0.53
PKM P14618 1/20 0.52
GAA P10253 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6407408 0.93 MEN1 (0.66) HCAR2KMT2AMEN1CASP3SENP8
SCHEMBL8044298 0.90 ALDH1A1 (0.60) HCAR2KMT2AMEN1CASP3SENP8
SCHEMBL14513318 0.89 MEN1 (0.61) HCAR2KMT2AMEN1CASP3SENP8
SCHEMBL6337230 0.89 KMT2A (0.53) HCAR2KMT2AALDH1A1KDM4ESMN1; SMN2
SCHEMBL5696409 0.88 ALDH1A1 (0.63) HCAR2KMT2AMEN1CASP3SENP8
SCHEMBL6582641 0.86 HCAR2 (0.62) HCAR2KMT2AMEN1CASP3SENP8
SCHEMBL14537776 0.86 MEN1 (0.57) HCAR2KMT2AMEN1CASP3SENP8
SCHEMBL6349058 0.83 MEN1 (0.54) HCAR2KMT2AMEN1CASP3SENP8
SCHEMBL29414340 0.83 HCAR2 (0.49) HCAR2KMT2AMEN1CASP3SENP8
SCHEMBL28743854 0.83 HCAR2 (0.49) HCAR2KMT2AMEN1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050027008-A1 Cancer remedy comprising anthranilic acid derivatives as active ingredient TEIJIN LIMITED 2005-02-03 US disclosed
US-20030220402-A1 Cancer remedy comprising anthranilic acid derivatives as active ingredients TEIJIN LIMITED (JP) 2003-11-27 US disclosed
EP-1256341-A1 CANCER REMEDY COMPRISING ANTHRANILIC ACID DERIVATIVE AS ACTIVE INGREDIENT TEIJIN LIMITED (JP) 2002-11-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030220402-A1 Cancer remedy comprising anthranilic acid derivatives as active ingredients HCCS, BCOR, CBR1 HCAR2 274/4885KMT2A 553/4885MEN1 3155/4885
US-20050027008-A1 Cancer remedy comprising anthranilic acid derivatives as active ingredient CA9, HCCS, CA7 HCAR2 387/4885KMT2A 799/4885MEN1 1552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.