SCHEMBL6582641

SCHEMBL6582641

O=C(Cc1ccc(Oc2ccc3cc(O)ccc3c2)nc1)Nc1ccccc1C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 14/20 0.62
MEN1 O00255 1/20 0.53
CASP3 P42574 1/20 0.53
KMT2A Q03164 1/20 0.53
SENP8 Q96LD8 1/20 0.53
SENP7 Q9BQF6 1/20 0.53
SENP6 Q9GZR1 1/20 0.53
CYP2C9 P11712 2/20 0.45
CYP2C8 P10632 1/20 0.45
ALDH1A1 P00352 4/20 0.44
KDM4E B2RXH2 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
LMNA P02545 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
PKM P14618 1/20 0.43
KDM6B O15054 1/20 0.42
KDM4D Q6B0I6 1/20 0.42
KDM4C Q9H3R0 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6340616 0.91 MEN1 (0.54) HCAR2MEN1CASP3KMT2ASENP8
SCHEMBL6349056 0.90 HCAR2 (0.49) HCAR2KMT2AALDH1A1KDM4ELMNA
SCHEMBL6401908 0.86 HCAR2 (0.67) HCAR2MEN1CASP3KMT2ASENP8
SCHEMBL6338905 0.83 KDM4E (0.47) HCAR2MEN1CASP3KMT2ASENP8
SCHEMBL6346488 0.82 CTSV (0.46) HCAR2MEN1CASP3KMT2ASENP8
SCHEMBL6341406 0.81 KMT2A (0.51) KMT2AALDH1A1KDM4ESMN1; SMN2LMNA
SCHEMBL6337646 0.80 ALDH1A1 (0.45) HCAR2MEN1CASP3KMT2ASENP8
SCHEMBL6340688 0.80 ALDH1A1 (0.42) HCAR2MEN1CASP3KMT2ASENP8
SCHEMBL6407408 0.80 MEN1 (0.66) HCAR2MEN1CASP3KMT2ASENP8
SCHEMBL6348822 0.78 CTSV (0.48) HCAR2MEN1CASP3KMT2ASENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1101755-B1 ANTHRANILIC ACID DERIVATIVES TEIJIN LTD (JP) 2004-10-06 EP disclosed