SCHEMBL6401924

SCHEMBL6401924

Nc1cccc(CS(=O)(=O)O)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.53
TDP1 Q9NUW8 2/20 0.53
TSHR P16473 1/20 0.53
HSD17B10 Q99714 1/20 0.53
MAOA P21397 2/20 0.50
MAOB P27338 2/20 0.50
CYP19A1 P11511 2/20 0.48
CA1 P00915 3/20 0.47
CA2 P00918 3/20 0.47
CA9 Q16790 3/20 0.47
LMNA P02545 1/20 0.47
CA12 O43570 2/20 0.45
CA14 Q9ULX7 2/20 0.45
CA4 P22748 1/20 0.45
CCR2 P41597 3/20 0.45
CYP3A4 P08684 1/20 0.44
CASP1 P29466 1/20 0.44
RECQL P46063 1/20 0.44
PRMT1 Q99873 1/20 0.42
F2 P00734 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30010246 1.00 ALDH1A1 (0.53) ALDH1A1TDP1TSHRHSD17B10MAOA
SCHEMBL30010872 0.88 ALDH1A1 (0.43) ALDH1A1TDP1TSHRHSD17B10MAOA
SCHEMBL23779534 0.85 MAOB (0.52) ALDH1A1TDP1TSHRHSD17B10MAOA
SCHEMBL29634429 0.85 MAOB (0.52) ALDH1A1TDP1TSHRHSD17B10MAOA
SCHEMBL8075846 0.84 CA2 (0.41) ALDH1A1CYP19A1CA1CA2CA9
SCHEMBL2464599 0.83 CA1 (0.59) ALDH1A1TDP1TSHRHSD17B10MAOA
SCHEMBL589307 0.83 MAOB (0.50) ALDH1A1TDP1TSHRHSD17B10MAOA
Sulfuric Acid SCHEMBL8646801 0.83 CA1 (0.60) ALDH1A1TDP1TSHRHSD17B10MAOA
SCHEMBL30279898 0.83 MAOB (0.50) ALDH1A1TDP1TSHRHSD17B10MAOA
Tetrabuthylammonium SCHEMBL8870078 0.83 TSHR (0.40) ALDH1A1TDP1TSHRHSD17B10MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0270804-B1 PROCESS FOR THE PREPARATION OF FINELY DIVIDED POLYISOCYANATES CONTAINING UREA GROUPS BAYER AG (DE) 1990-09-26 EP claimed
US-4757105-A Reacting water with organic polyisocyanate in the presence of an amine-containing emulsion stabilizer BAYER AKTIENGESELLSCHAFT (DE) 1988-07-12 US claimed
EP-0270804-A1 Process for the preparation of finely divided polyisocyanates containing urea groups BAYER AG (DE) 1988-06-15 EP claimed
CN-1215052-C Sulfonic acid derivatives of hydroxamic acids and their use as medicinal products MITSUBISHI PHARMACEUTICAL CO L (JP) 2005-08-17 CN disclosed
EP-1501830-A1 7-ARYL-3,9-DIAZABICYCLO[3.3.1]NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES Actelion Pharmaceuticals Ltd. (CH) 2005-02-02 EP disclosed
WO-2003093267-A1 7-ARYL-3,9-DIAZABICYCLO(3.3.1)NON-6-ENE DERIVATIVES AND THEIR USE AS RENIN INHIBITORS IN THE TREATMENT OF HYPERTENSION, CARDIOVASCULAR OR RENAL DISEASES ACTELION PHARMACEUTICALS LTD (CH) 2003-11-13 WO disclosed
CN-1443158-A Sulfonic acid derivatives of hydroxamic acids and their use as medicinal products MITSUBISHI PHARMACEUTICAL CO L (JP) 2003-09-17 CN disclosed
US-5770707-A COLORFAST REACTIVE DYES FOR COTTON SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-06-23 US disclosed
US-5610144-A CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS RHONE-POULENC RORER S.A. (FR) 1997-03-11 US disclosed
US-5596083-A CELLULOSE, POLYAMIDES, POLYURETHANES OR LEATHER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-01-21 US disclosed
EP-0728817-A2 Monoazo compounds and dyeing or printing methods using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-08-28 EP disclosed
EP-0270804-B1 PROCESS FOR THE PREPARATION OF FINELY DIVIDED POLYISOCYANATES CONTAINING UREA GROUPS BAYER AG (DE) 1990-09-26 EP disclosed
EP-0190947-B1 PROCESS FOR PRODUCING AZO PIGMENTS Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo (JP) 1990-01-31 EP disclosed
US-4757105-A Reacting water with organic polyisocyanate in the presence of an amine-containing emulsion stabilizer BAYER AKTIENGESELLSCHAFT (DE) 1988-07-12 US disclosed
EP-0270804-A1 Process for the preparation of finely divided polyisocyanates containing urea groups BAYER AG (DE) 1988-06-15 EP disclosed
US-4617382-A PRINTING; DYEING; SILK, LEATHER, WOOL AND POLYAMIDES CIBA-GEIGY CORPORATION (US) 1986-10-14 US disclosed
US-4337195-A FOR DYEING COTTON AND HAVING GOOD COLORFASTNESS BAYER AKTIENGESELLSCHAFT (DE) 1982-06-29 US disclosed
US-4219473-A Substituted unsymmetrical azo, azomethine 1:2 chromium complexes CIBA-GEIGY CORPORATION (US) 1980-08-26 US disclosed
US-4053462-A UNSYMMETRICAL PHENYL AZO NAPHTHYL CHROMIUM COMPLEX DYES CIBA-GEIGY CORPORATION (US) 1977-10-11 US disclosed
US-4005065-A GOOD FASTNESS TO LIGHT, PERSPIRATION, FULLING, DECATIZING AND CARBONIZING CIBA-GEIGY CORPORATION (US) 1977-01-25 US disclosed