SCHEMBL6402127

SCHEMBL6402127

Fc1c(F)c(-c2ccccc2)c(-c2ccccc2)c(-c2ccccc2)c1F

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.46
MAPT P10636 1/20 0.46
HTT P42858 1/20 0.46
ALDH1A1 P00352 2/20 0.44
TYMP P19971 1/20 0.40
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39
DHODH Q02127 4/20 0.38
ACHE P22303 2/20 0.35
EGFR P00533 1/20 0.35
GRM5 P41594 1/20 0.35
MAP2 P11137 2/20 0.35
MAPK1 P28482 2/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
KIF11 P52732 1/20 0.35
CHEK1 O14757 1/20 0.33
AKT2 P31751 1/20 0.33
DHFR P00374 1/20 0.33
BRD4 O60885 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7713106 0.97 LMNA (0.48) LMNAMAPTHTTALDH1A1TYMP
SCHEMBL17747946 0.97 LMNA (0.48) LMNAMAPTHTTALDH1A1TYMP
SCHEMBL247368 0.91 LMNA (0.48) LMNAMAPTHTTALDH1A1TYMP
SCHEMBL7704707 0.88 LMNA (0.46) LMNAMAPTHTTALDH1A1TYMP
SCHEMBL7711087 0.88 ALDH1A1 (0.50) LMNAMAPTHTTALDH1A1TYMP
SCHEMBL31305580 0.86 LMNA (0.43) LMNAMAPTHTTALDH1A1TYMP
SCHEMBL14182621 0.85 LMNA (0.48) LMNAMAPTHTTALDH1A1TYMP
SCHEMBL11454320 0.84 NPC1 (0.41) LMNAMAPTHTTALDH1A1DHODH
SCHEMBL27716599 0.83 LMNA (0.42) LMNAMAPTHTTALDH1A1TYMP
SCHEMBL1179753 0.81 ALDH1A1 (0.50) LMNAMAPTHTTALDH1A1TYMP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3031856-B1 CROSSLINKABLE FLUORINATED ELASTOMER COMPOSITION AND CROSSLINKED PRODUCT THEREOFa AGC INC (JP) 2019-07-10 EP claimed
US-10087128-B2 Fluorinated aromatic compound, method for its production, curable material, its cured product, and optical member AGC Inc. (JP) 2018-10-02 US claimed
US-10066077-B2 Crosslinkable fluorinated elastomer composition and crosslinked product thereof ASAHI GLASS COMPANY, LIMITED (JP) 2018-09-04 US claimed
EP-3031793-B1 FLUORINATED AROMATIC COMPOUND, METHOD FOR ITS PRODUCTION, CURABLE MATERIAL, ITS CURED PRODUCT, AND OPTICAL MEMBER ASAHI GLASS CO LTD (JP) 2018-03-21 EP claimed
EP-3031856-A1 FLUORINE-CONTAINING CROSSLINKABLE ELASTOMER COMPOSITION AND CROSSLINKED PRODUCT THEREOF Asahi Glass Company, Limited (JP) 2016-06-15 EP claimed
EP-3031793-A1 FLUORINE-CONTAINING AROMATIC COMPOUND, METHOD FOR PRODUCING SAME, CURABLE MATERIAL, CURED PRODUCT THEREOF, AND OPTICAL MEMBER Asahi Glass Company, Limited (JP) 2016-06-15 EP claimed
US-20160137809-A1 CROSSLINKABLE FLUORINATED ELASTOMER COMPOSITION AND CROSSLINKED PRODUCT THEREOF ASAHI GLASS COMPANY, LIMITED (JP) 2016-05-19 US claimed
US-20160137572-A1 FLUORINATED AROMATIC COMPOUND, METHOD FOR ITS PRODUCTION, CURABLE MATERIAL, ITS CURED PRODUCT, AND OPTICAL MEMBER ASAHI GLASS COMPANY, LIMITED (JP) 2016-05-19 US claimed
US-20230114706-A1 PLASTIC OPTICAL FIBER MANUFACTURING METHOD NITTO DENKO CORPORATION (JP) 2023-04-13 US disclosed
CN-115362397-A Method for manufacturing plastic optical fiber 日东电工株式会社 2022-11-18 CN disclosed
EP-3031856-B1 CROSSLINKABLE FLUORINATED ELASTOMER COMPOSITION AND CROSSLINKED PRODUCT THEREOFa AGC INC (JP) 2019-07-10 EP disclosed
US-10087128-B2 Fluorinated aromatic compound, method for its production, curable material, its cured product, and optical member AGC Inc. (JP) 2018-10-02 US disclosed
US-10066077-B2 Crosslinkable fluorinated elastomer composition and crosslinked product thereof ASAHI GLASS COMPANY, LIMITED (JP) 2018-09-04 US disclosed
EP-3031793-B1 FLUORINATED AROMATIC COMPOUND, METHOD FOR ITS PRODUCTION, CURABLE MATERIAL, ITS CURED PRODUCT, AND OPTICAL MEMBER ASAHI GLASS CO LTD (JP) 2018-03-21 EP disclosed
US-20150247985-A1 Monolithic Polymer Optical Fiber Ribbon CHROMIS FIBEROPTICS, INC. 2015-09-03 US disclosed
US-9046670-B2 Monolithic polymer optical fiber ribbon CHROMIS FIBEROPTICS, INC. (US) 2015-06-02 US disclosed
US-20140341519-A1 MONOLITHIC POLYMER OPTICAL FIBER RIBBON CHROMIS FIBEROPTICS, INC. 2014-11-20 US disclosed
EP-2769255-A1 MONOLITHIC POLYMER OPTICAL FIBER RIBBON Chromis Fiberoptics Inc. (US) 2014-08-27 EP disclosed
WO-2013059601-A1 MONOLITHIC POLYMER OPTICAL FIBER RIBBON CHROMIS FIBEROPTICS, INC. (US) 2013-04-25 WO disclosed
US-20050141834-A1 Optical fiber having sea and islands structure ASAHI GLASS COMPANY, LIMITED (JP) 2005-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160137572-A1 FLUORINATED AROMATIC COMPOUND, METHOD FOR ITS PRODUCTION, CURABLE MATERIAL, ITS CURED PRODUCT, AND OPTICAL MEMBER AFF1, AFF2, AFF4 LMNA 1454/4885MAPT 2767/4885HTT 3015/4885
US-10087128-B2 Fluorinated aromatic compound, method for its production, curable material, its cured product, and optical member AFF1, AFF2, AFF4 LMNA 1454/4885MAPT 2767/4885HTT 3015/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.