Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.74 |
| ▸ | LMNA | P02545 | 4/20 | 0.74 |
| ▸ | PKM | P14618 | 2/20 | 0.74 |
| ▸ | HPGD | P15428 | 2/20 | 0.74 |
| ▸ | TSHR | P16473 | 2/20 | 0.74 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15983422 | 0.88 | ALDH1A1 (0.80) | ALDH1A1KDM4ELMNAPKMHPGD | |
| SCHEMBL4215001 | 0.88 | ALDH1A1 (0.71) | ALDH1A1KDM4ELMNAPKMHPGD | |
| SCHEMBL18556569 | 0.86 | ALDH1A1 (1.00) | ALDH1A1KDM4ELMNAPKMHPGD | |
| SCHEMBL6403236 | 0.83 | MAPK1 (0.62) | ALDH1A1KDM4ELMNAPKMHPGD | |
| SCHEMBL15983644 | 0.80 | ALDH1A1 (0.77) | ALDH1A1KDM4ELMNAHPGDTSHR | |
| SCHEMBL6407161 | 0.80 | ALDH1A1 (0.71) | ALDH1A1KDM4ELMNATSHRMAPT | |
| SCHEMBL15983430 | 0.78 | ALDH1A1 (0.64) | ALDH1A1KDM4ELMNATSHRMAPT | |
| SCHEMBL4210255 | 0.78 | ALDH1A1 (0.73) | ALDH1A1LMNATSHRMAPTL3MBTL1 | |
| SCHEMBL4211826 | 0.78 | ALDH1A1 (1.00) | ALDH1A1KDM4ELMNATSHRMAPT | |
| SCHEMBL6061302 | 0.78 | ALDH1A1 (0.74) | ALDH1A1KDM4ELMNAHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | ALDH1A1 720/4885KDM4E 3676/4885LMNA 4116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.