Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | METAP2 | P50579 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | TERT | O14746 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27940234 | 0.87 | SMN1; SMN2 (0.73) | MAPK1ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL11511053 | 0.84 | MAPK1 (0.79) | MAPK1ALDH1A1LMNAKDM4EMETAP2 | |
| SCHEMBL6402415 | 0.83 | ALDH1A1 (0.74) | ALDH1A1LMNAKDM4EPKMHPGD | |
| SCHEMBL4215001 | 0.82 | ALDH1A1 (0.71) | MAPK1ALDH1A1LMNAKDM4EPKM | |
| SCHEMBL6404125 | 0.78 | GAA (0.71) | MAPK1ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL6410613 | 0.78 | KMT2A (0.76) | MAPK1ALDH1A1LMNATSHRHTT | |
| SCHEMBL27940235 | 0.78 | ALDH1A1 (0.71) | MAPK1ALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL14427600 | 0.77 | MAPK1 (0.71) | MAPK1ALDH1A1LMNAKDM4EHTT | |
| SCHEMBL15983421 | 0.77 | MAPK1 (1.00) | MAPK1ALDH1A1LMNAKDM4ETSHR | |
| SCHEMBL27952226 | 0.77 | MAPK1 (0.71) | MAPK1ALDH1A1LMNAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | MAPK1 4613/4885ALDH1A1 720/4885LMNA 4116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.