Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CRHBP | P24387 | 1/20 | 0.50 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 5/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6403646 | 0.98 | SMN1; SMN2 (0.49) | SMN1; SMN2CRHBPCRHR2CYP1A2CYP2D6 | |
| SCHEMBL13779832 | 0.84 | HRH4 (0.57) | SMN1; SMN2CRHBPCRHR2CYP1A2MAPT | |
| SCHEMBL908493 | 0.82 | MAPT (0.71) | SMN1; SMN2CRHBPCRHR2CYP1A2CYP2D6 | |
| SCHEMBL1505630 | 0.82 | HRH4 (0.56) | HRH4 | |
| SCHEMBL1320033 | 0.81 | CYP1A2 (0.70) | SMN1; SMN2CRHBPCRHR2CYP1A2CYP2D6 | |
| SCHEMBL1318490 | 0.81 | CYP1A2 (0.70) | SMN1; SMN2CRHBPCRHR2CYP1A2CYP2D6 | |
| SCHEMBL8695421 | 0.81 | HRH4 (0.56) | SMN1; SMN2CRHBPCRHR2CYP1A2HRH4 | |
| SCHEMBL24215218 | 0.80 | CYP1A2 (0.43) | CYP1A2CYP2D6MAPTLMNATSHR | |
| SCHEMBL3719291 | 0.79 | MAPT (0.72) | SMN1; SMN2CRHBPCRHR2CYP1A2CYP2D6 | |
| SCHEMBL6017340 | 0.78 | CHRM3 (0.47) | SMN1; SMN2CRHBPCRHR2CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1235565-B1 | USE OF 5HT 3 AGONISTS FOR RELAXING THE FUNDUS | JANSSEN PHARMACEUTICA NV (BE) | 2005-12-28 | — | — | EP | claimed |
| US-20050209270-A1 | Use of 5HT3 agonists for relaxing the fundus | MEULEMANS ANN LOUISE G | 2005-09-22 | — | — | US | claimed |
| US-20050119297-A1 | Use of 5HT3 agonists for relaxing the fundus | MEULEMANS ANN L G (BE) | 2005-06-02 | — | — | US | claimed |
| US-11530193-B2 | Kinase inhibitors | THE UNIVERSITY OF MANCHESTER (GB) | 2022-12-20 | — | — | US | disclosed |
| CN-114144226-A | Percutaneous spinal cord electrical nerve modulator and application thereof | 加利福尼亚大学董事会 | 2022-03-04 | — | — | CN | disclosed |
| EP-3793996-A1 | KINASE INHIBITORS | The University of Manchester (GB) | 2021-03-24 | — | — | EP | disclosed |
| CN-112119077-A | Kinase inhibitors | 曼彻斯特大学 | 2020-12-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11530193-B2 | Kinase inhibitors | CAMKK2, CAMK1, CAMKK1 | SMN1; SMN2 3705/4885CRHBP 2997/4885CRHR2 2526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.