Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | DDO | Q99489 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13485647 | 0.79 | AHR (0.59) | AHRDAODDORAB9AALDH1A1 | |
| SCHEMBL5808418 | 0.79 | MEN1 (0.42) | AHRRAB9AALDH1A1HSD17B10GPR3 | |
| SCHEMBL1917841 | 0.77 | AHR (0.57) | AHRCYP2D6DAODDORAB9A | |
| SCHEMBL632968 | 0.77 | KDM4E (0.50) | CYP2D6RAB9AALDH1A1HSD17B10MEN1 | |
| SCHEMBL1101269 | 0.76 | ALDH1A1 (0.42) | RAB9AALDH1A1HSD17B10GPR3MEN1 | |
| SCHEMBL11785843 | 0.76 | MEN1 (0.66) | ALDH1A1HSD17B10GPR3MEN1KMT2A | |
| Alcohol SCHEMBL6430442 | 0.76 | MEN1 (0.40) | CYP2D6RAB9AALDH1A1HSD17B10GPR3 | |
| SCHEMBL13301938 | 0.76 | AHR (0.55) | AHRDAODDORAB9AALDH1A1 | |
| SCHEMBL6953567 | 0.76 | AHR (0.55) | AHRDAODDORAB9AALDH1A1 | |
| SCHEMBL6402986 | 0.75 | MAPT (0.59) | AHRALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6872835-B2 | Process for preparation of fused pyrroles | JAPAN SCIENCE & TECHNOLOGY CORPORATION (JP) | 2005-03-29 | — | — | US | disclosed |
| EP-1302459-B1 | PROCESSES FOR PREPARATION OF FUSED PYRROLES | JAPAN SCIENCE & TECH AGENCY (JP) | 2004-10-27 | — | — | EP | disclosed |
| US-20040049054-A1 | Process for preparation of fused pyrroles | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2004-03-11 | — | — | US | disclosed |
| EP-1302459-A1 | PROCESSES FOR PREPARATION OF FUSED PYRROLES | Japan Science and Technology Corporation (JP) | 2003-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040049054-A1 | Process for preparation of fused pyrroles | IDO1, IDO2, PAH | AHR 46/4885CYP2D6 1220/4885DAO 573/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.