Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | AHR | P35869 | 1/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
| ▸ | KRAS | P01116 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953891 | 0.82 | MAPT (0.59) | MAPTCYP3A4ALDH1A1HTTTSHR | |
| SCHEMBL1781653 | 0.82 | MAPT (0.59) | MAPTCYP3A4ALDH1A1HTTTSHR | |
| SCHEMBL25658191 | 0.81 | KDM4E (0.64) | MAPTCYP3A4ALDH1A1HTTTSHR | |
| SCHEMBL3646517 | 0.80 | KDM4E (0.62) | MAPTCYP3A4ALDH1A1HTTTSHR | |
| SCHEMBL28181864 | 0.80 | CHRNB2 (0.43) | MAPTCYP3A4ALDH1A1HTTTSHR | |
| SCHEMBL4423600 | 0.79 | MAPT (0.65) | MAPTCYP3A4ALDH1A1HTTTSHR | |
| SCHEMBL18383120 | 0.79 | MAPT (0.69) | MAPTCYP3A4ALDH1A1HTTTSHR | |
| SCHEMBL1077319 | 0.79 | ALDH1A1 (0.40) | MAPTCYP3A4ALDH1A1HTTTSHR | |
| SCHEMBL14246882 | 0.77 | HTR2A (0.54) | — | |
| SCHEMBL669111 | 0.77 | HTT (0.73) | MAPTCYP3A4ALDH1A1HTTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344279-B | Synthesis method of indole C2 benzyl C-H bond direct amine methylation | 山东第二医科大学 | 2024-08-30 | — | — | CN | disclosed |
| CN-118344279-A | Synthesis method of indole C2 benzyl C-H bond direct amine methylation | 山东第二医科大学 | 2024-07-16 | — | — | CN | disclosed |
| US-6872835-B2 | Process for preparation of fused pyrroles | JAPAN SCIENCE & TECHNOLOGY CORPORATION (JP) | 2005-03-29 | — | — | US | disclosed |
| EP-1302459-B1 | PROCESSES FOR PREPARATION OF FUSED PYRROLES | JAPAN SCIENCE & TECH AGENCY (JP) | 2004-10-27 | — | — | EP | disclosed |
| US-20040049054-A1 | Process for preparation of fused pyrroles | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2004-03-11 | — | — | US | disclosed |
| EP-1302459-A1 | PROCESSES FOR PREPARATION OF FUSED PYRROLES | Japan Science and Technology Corporation (JP) | 2003-04-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040049054-A1 | Process for preparation of fused pyrroles | IDO1, IDO2, PAH | MAPT 3087/4885CYP3A4 230/4885ALDH1A1 1591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.