Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.43 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6403880 | 0.86 | TDP1 (0.51) | TDP1LMNAMEN1KMT2APOLB | |
| SCHEMBL6403819 | 0.84 | TDP1 (0.52) | ALDH1A1TDP1MAPTKDM4EROCK2 | |
| SCHEMBL6402399 | 0.82 | TDP1 (0.49) | ALDH1A1HPGDTDP1MAPTLMNA | |
| SCHEMBL6409368 | 0.81 | TDP1 (0.52) | ALDH1A1TDP1MAPTLMNAKDM4E | |
| SCHEMBL6410547 | 0.81 | NPC1 (0.55) | ALDH1A1TDP1LMNAKDM4EMEN1 | |
| SCHEMBL6404261 | 0.79 | TDP1 (0.50) | ALDH1A1TDP1MAPTLMNATP53 | |
| SCHEMBL6404273 | 0.79 | HPGD (0.49) | ALDH1A1HPGDTDP1MAPTLMNA | |
| SCHEMBL6406598 | 0.79 | LMNA (0.61) | ALDH1A1HPGDTDP1LMNAMEN1 | |
| SCHEMBL6404220 | 0.77 | KMT2A (0.50) | ALDH1A1TDP1ROCK2MEN1KMT2A | |
| SCHEMBL6403149 | 0.76 | NPC1 (0.57) | ALDH1A1TDP1MAPTLMNAROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | ALDH1A1 1486/4885HPGD 3244/4885TDP1 1721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.