Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.62 |
| ▸ | RAB9A | P51151 | 7/20 | 0.62 |
| ▸ | NPC1 | O15118 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | ABL1 | P00519 | 1/20 | 0.60 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6404864 | 0.78 | SMN1; SMN2 (0.53) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL9667165 | 0.75 | RAB9A (0.68) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL3429462 | 0.75 | SMN1; SMN2 (1.00) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL11130494 | 0.75 | NPC1 (0.65) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL3065316 | 0.74 | SMN1; SMN2 (0.69) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL3079520 | 0.74 | SMN1; SMN2 (0.83) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL6408107 | 0.73 | ALDH1A1 (0.67) | SMN1; SMN2RAB9ANPC1ALDH1A1LMNA | |
| SCHEMBL6485274 | 0.73 | NPC1 (0.73) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL11887629 | 0.72 | NPC1 (0.69) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL9665950 | 0.72 | RAB9A (0.63) | SMN1; SMN2RAB9ANPC1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | SMN1; SMN2 4793/4885RAB9A 4278/4885NPC1 2070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.