Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.51 |
| ▸ | DRD3 | P35462 | 4/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | TERT | O14746 | 5/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6403375 | 0.89 | TSHR (0.47) | DRD2DRD3RAB9AMAPK1MEN1 | |
| SCHEMBL6405947 | 0.86 | DRD2 (0.53) | DRD2DRD3ALDH1A1MAPK1MEN1 | |
| SCHEMBL6408474 | 0.84 | TSHR (0.55) | DRD2DRD3ALDH1A1TSHR | |
| SCHEMBL6408452 | 0.84 | TSHR (0.62) | DRD2DRD3TSHR | |
| SCHEMBL6402203 | 0.84 | TSHR (0.46) | DRD2DRD3MAPK1TSHRL3MBTL1 | |
| SCHEMBL6402376 | 0.83 | TSHR (0.50) | DRD2DRD3ALDH1A1KMT2ATSHR | |
| SCHEMBL6403506 | 0.82 | L3MBTL1 (0.60) | DRD2DRD3ALDH1A1MAPK1TSHR | |
| SCHEMBL6407795 | 0.81 | TSHR (0.48) | DRD2DRD3ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL6409759 | 0.81 | TSHR (0.56) | DRD2DRD3ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL6404682 | 0.81 | DRD3 (0.50) | DRD2DRD3ALDH1A1MAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | DRD2 3842/4885DRD3 2876/4885KCNH2 2873/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.