Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 12/20 | 0.60 |
| ▸ | MMP9 | P14780 | 1/20 | 0.60 |
| ▸ | MMP8 | P22894 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.51 |
| ▸ | GAA | P10253 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | GLA | P06280 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.51 |
| ▸ | RELA | Q04206 | 3/20 | 0.51 |
| ▸ | GFER | P55789 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10873450 | 0.89 | MAPT (0.73) | APPMMP9MMP8MAPTKDM4E | |
| SCHEMBL3385440 | 0.88 | KDM4E (0.50) | APPMMP9MMP8MAPTKDM4E | |
| SCHEMBL28174501 | 0.85 | APP (0.58) | APPMMP9MMP8MAPTKDM4E | |
| SCHEMBL3680730 | 0.83 | SMN1; SMN2 (0.60) | APPMMP9MMP8MAPTKDM4E | |
| SCHEMBL8535704 | 0.83 | ALDH1A1 (0.60) | APPMMP9MMP8MAPTKDM4E | |
| SCHEMBL6396202 | 0.83 | MAPT (0.65) | APPMMP9MMP8MAPTKDM4E | |
| SCHEMBL7455542 | 0.82 | APP (0.55) | APPMMP9MMP8MAPTKDM4E | |
| 2-Phenylbenzo[D]Thiazole SCHEMBL12479298 | 0.81 | APP (0.62) | APPMMP9MMP8MAPTKDM4E | |
| SCHEMBL27307376 | 0.81 | PRKDC (0.48) | APPMMP9MMP8NPC1RAB9A | |
| SCHEMBL1983852 | 0.80 | CYP3A4 (0.63) | APPMMP9MMP8MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050079185-A1 | Vaccine formulations | MERIAL, INC. | 2005-04-14 | — | — | US | claimed |
| US-20050170077-A1 | Adhesion method | SHIPLEY COMPANY, L.L.C. (US) | 2005-08-04 | — | — | US | disclosed |
| US-20040161545-A1 | Adhesion method | SHIPLEY COMPANY, L.L.C. | 2004-08-19 | — | — | US | disclosed |
| EP-0464371-A1 | Polyamic acid structures, and methods of fabrication thereof | International Business Machines Corporation (US) | 1992-01-08 | — | — | EP | disclosed |
| US-5004627-A | Polyimides for mold release | ETHYL CORPORATION (US) | 1991-04-02 | — | — | US | disclosed |
| EP-0192937-B1 | FLEXIBLE POLYIMIDE MULTILAYER LAMINATE | Akzo Patente GmbH (DE) | 1990-10-24 | — | — | EP | disclosed |
| EP-0249744-B1 | PROCESS FOR MAKING POLYIMIDE-METAL LAMINATES | AKZO N.V. (NL) | 1989-10-11 | — | — | EP | disclosed |
| EP-0167020-B1 | FLEXIBLE POLYIMIDE MULTILAYER LAMINATE | Akzo Patente GmbH (DE) | 1988-11-23 | — | — | EP | disclosed |
| US-4746561-A | Polyimide-containing cover layer for a printed circuit element | AKZO N.V. (NL) | 1988-05-24 | — | — | US | disclosed |
| EP-0249744-A1 | Process for making polyimide-metal laminates | AKZO N.V. (NL) | 1987-12-23 | — | — | EP | disclosed |
| EP-0116297-B1 | POLYIMIDE LAMINATE WITH PEEL-RESISTANCE AND METHOD OF MANUFACTURING IT | Akzo GmbH (DE) | 1987-12-02 | — | — | EP | disclosed |
| US-4705720-A | FOR PRINTED CIRCUITS | AKZO NV (NL) | 1987-11-10 | — | — | US | disclosed |
| US-4699841-A | PRINTED CIRCUITS | AKZO NV (NL) | 1987-10-13 | — | — | US | disclosed |
| US-4675246-A | DIRECT BONDING WITH SUBSTRATE AND POLYIMIDE | AKZO NV (NL) | 1987-06-23 | — | — | US | disclosed |
| EP-0194413-A2 | Printed circuit element with a cover sheet containing polyimide | Akzo Patente GmbH (DE) | 1986-09-17 | — | — | EP | disclosed |
| EP-0167020-A2 | Flexible polyimide multilayer laminate | Akzo Patente GmbH (DE) | 1986-01-08 | — | — | EP | disclosed |
| US-4522880-A | EXTRUSION ON SUBSTRATE, THEN CURING | AKZONA INCORPORATED (US) | 1985-06-11 | — | — | US | disclosed |
| EP-0116297-A2 | Polyimide laminate with peel-resistance and method of manufacturing it | Akzo GmbH (DE) | 1984-08-22 | — | — | EP | disclosed |