SCHEMBL6403918

SCHEMBL6403918

COc1cccc(OC)c1C(=O)[PH](=O)CCCCC(=O)c1c(C)cccc1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
TAS1R3 Q7RTX0 1/20 0.39
TAS1R1 Q7RTX1 1/20 0.39
TAS1R2 Q8TE23 1/20 0.39
ATM Q13315 2/20 0.39
HDAC1 Q13547 2/20 0.38
HDAC8 Q9BY41 1/20 0.38
HDAC6 Q9UBN7 1/20 0.37
MAPT P10636 3/20 0.36
ALDH1A1 P00352 2/20 0.36
HTT P42858 2/20 0.36
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36
PPARA Q07869 1/20 0.35
KCNB1 Q14721 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5995533 0.91 CA12 (0.42) CA12CA1CA2CA7CA9
SCHEMBL6405223 0.86 LMNA (0.37) TAS1R3TAS1R1TAS1R2ATMHDAC1
SCHEMBL28861053 0.84 L3MBTL1 (0.50) CA12CA1CA2CA7CA9
SCHEMBL5997089 0.82 CA12 (0.40) CA12CA1CA2CA7CA9
SCHEMBL5996385 0.81 CYP2D6 (0.41) ATMMAPTALDH1A1LMNAMEN1
SCHEMBL23152411 0.80 PPARA (0.55) CA12CA1CA2CA7CA9
SCHEMBL27874200 0.79 PPARA (0.50) CA12CA1CA2CA7CA9
SCHEMBL5995486 0.79 CA12 (0.37) CA12CA1CA2CA7CA9
SCHEMBL6402068 0.79 MEN1 (0.39) ATMHDAC1HDAC8HDAC6MAPT
SCHEMBL14032169 0.79 CA12 (0.44) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6969733-B2 Photoinitiators CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-11-29 US disclosed
US-20030139485-A1 Photoinitiators WOLF JEAN-PIERRE (CH) 2003-07-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030139485-A1 Photoinitiators DHCR24, NR1I3, CBR1 CA12 2616/4885CA1 3491/4885CA2 2861/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.