Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6407914 | 0.86 | RAB9A (0.48) | RAB9ANPC1TDP1SMN1; SMN2MEN1 | |
| SCHEMBL6409350 | 0.83 | SMN1; SMN2 (0.39) | RAB9ANPC1TDP1SMN1; SMN2L3MBTL1 | |
| SCHEMBL6407567 | 0.78 | KMT2A (0.55) | RAB9ANPC1TDP1MAPTSMN1; SMN2 | |
| SCHEMBL6407948 | 0.78 | BCHE (0.45) | RAB9ANPC1TDP1MAPTSMN1; SMN2 | |
| SCHEMBL6404107 | 0.76 | SMN1; SMN2 (0.53) | RAB9ASMN1; SMN2L3MBTL1MEN1KMT2A | |
| SCHEMBL6405950 | 0.76 | NPC1 (0.55) | RAB9ANPC1SMN1; SMN2GRM5MEN1 | |
| SCHEMBL6404106 | 0.76 | SMN1; SMN2 (0.53) | RAB9ASMN1; SMN2L3MBTL1MEN1KMT2A | |
| SCHEMBL6403210 | 0.76 | EPHX1 (0.51) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL6407407 | 0.75 | EPHX1 (0.53) | RAB9ANPC1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL6403186 | 0.72 | KMT2A (0.53) | RAB9ANPC1TDP1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | RAB9A 4044/4885NPC1 1915/4885TDP1 1721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.