Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 8/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | RGS12 | O14924 | 1/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4207066 | 0.92 | RAB9A (0.63) | RAB9ASMN1; SMN2NPC1KMT2AMAPT | |
| SCHEMBL4205993 | 0.86 | RAB9A (0.62) | RAB9ASMN1; SMN2NPC1KMT2AMAPT | |
| SCHEMBL4200868 | 0.78 | RAB9A (0.66) | RAB9ASMN1; SMN2NPC1KMT2AMAPT | |
| SCHEMBL4206014 | 0.78 | ALDH1A1 (0.79) | RAB9ASMN1; SMN2NPC1KMT2AMAPT | |
| SCHEMBL16944479 | 0.76 | SMN1; SMN2 (1.00) | RAB9ASMN1; SMN2NPC1KMT2AMAPT | |
| SCHEMBL4212033 | 0.76 | ALDH1A1 (0.70) | RAB9ASMN1; SMN2NPC1KMT2AMAPT | |
| SCHEMBL4197148 | 0.75 | NPC1 (0.81) | RAB9ASMN1; SMN2NPC1KMT2AMAPT | |
| SCHEMBL4203625 | 0.72 | RAB9A (0.60) | RAB9ASMN1; SMN2NPC1KMT2AMAPT | |
| SCHEMBL4217085 | 0.72 | MAPT (0.55) | RAB9ASMN1; SMN2NPC1KMT2AMAPT | |
| SCHEMBL4206403 | 0.71 | SMN1; SMN2 (0.59) | RAB9ASMN1; SMN2NPC1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | RAB9A 4278/4885SMN1; SMN2 4793/4885NPC1 2070/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.