Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.72 |
| ▸ | VCP | P55072 | 7/20 | 0.66 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6404099 | 0.92 | NPSR1 (0.65) | SIRT2VCPNPSR1MAPTCYP1A2 | |
| SCHEMBL16409978 | 0.84 | SIRT2 (1.00) | SIRT2VCPNPSR1MAPTCYP1A2 | |
| SCHEMBL6406624 | 0.82 | TSHR (0.64) | SIRT2VCPNPSR1MAPTCYP1A2 | |
| SCHEMBL31160453 | 0.77 | ALDH1A1 (0.52) | SIRT2NPSR1MAPTCYP1A2CYP3A4 | |
| SCHEMBL11887417 | 0.77 | KMT2A (0.80) | SIRT2VCPNPSR1MAPTCYP1A2 | |
| SCHEMBL17679308 | 0.76 | SIRT2 (1.00) | SIRT2VCPNPSR1MAPTCYP1A2 | |
| SCHEMBL16409996 | 0.74 | SIRT2 (1.00) | SIRT2VCPNPSR1MAPTCYP1A2 | |
| SCHEMBL31160427 | 0.74 | HPGD (0.51) | SIRT2NPSR1MAPTCYP1A2CYP3A4 | |
| SCHEMBL11887418 | 0.71 | MAPT (0.71) | SIRT2VCPNPSR1MAPTCYP1A2 | |
| SCHEMBL6403236 | 0.70 | MAPK1 (0.62) | NPSR1MAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | SIRT2 2635/4885VCP 876/4885NPSR1 4536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.