Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.55 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6404869 | 0.88 | GAA (0.56) | GAATSHRHTTHSD17B10NPC1 | |
| SCHEMBL4744658 | 0.87 | GAA (0.66) | GAATSHRHTTHSD17B10NPC1 | |
| SCHEMBL4649301 | 0.87 | GAA (0.70) | GAATSHRHTTHSD17B10NPC1 | |
| SCHEMBL4649479 | 0.87 | GAA (0.54) | GAATSHRHTTHSD17B10NPC1 | |
| SCHEMBL6405657 | 0.84 | GAA (0.52) | GAATSHRHTTHSD17B10NPC1 | |
| SCHEMBL6406082 | 0.82 | GAA (0.68) | GAATSHRHTTHSD17B10ALOX15 | |
| SCHEMBL6409001 | 0.82 | ADORA2B (0.53) | GAATSHRHTTHSD17B10ALDH1A1 | |
| SCHEMBL6406084 | 0.79 | RAB9A (0.48) | GAATSHRHTTHSD17B10ALOX15 | |
| SCHEMBL4646857 | 0.76 | CREBBP (0.65) | GAATSHRHTTNPC1ALDH1A1 | |
| SCHEMBL6405653 | 0.76 | TSHR (0.55) | GAATSHRHTTHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050282838-A1 | Compounds, compositions, and methods | CYTOKINETICS, INC. | 2005-12-22 | — | — | US | claimed |
| US-20050282838-A1 | Compounds, compositions, and methods | CYTOKINETICS, INC. | 2005-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282838-A1 | Compounds, compositions, and methods | PCNA, MKI67, TP53 | GAA 349/4885TSHR 4678/4885HTT 1612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.