Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | CDC25A | P30304 | 2/20 | 0.59 |
| ▸ | CDC25B | P30305 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4216773 | 0.84 | CDC25A (0.69) | ALDH1A1KMT2ACDC25ACDC25BMAPT | |
| SCHEMBL4200737 | 0.84 | ALDH1A1 (0.73) | ALDH1A1KMT2ACDC25ACDC25BMAPT | |
| SCHEMBL6410921 | 0.83 | NPC1 (0.67) | ALDH1A1KMT2ACDC25ACDC25BMAPT | |
| SCHEMBL27809458 | 0.81 | ALDH1A1 (0.63) | ALDH1A1KMT2AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL4210989 | 0.80 | SMN1; SMN2 (0.64) | KMT2AMAPTSMN1; SMN2KDM4EPTGES | |
| SCHEMBL4206060 | 0.80 | CDC25A (0.67) | ALDH1A1KMT2ACDC25ACDC25BMAPT | |
| SCHEMBL29623117 | 0.79 | CDC25A (0.65) | ALDH1A1KMT2ACDC25ACDC25BMAPT | |
| SCHEMBL6404782 | 0.79 | ALDH1A1 (0.69) | ALDH1A1KMT2ACDC25ACDC25BMAPT | |
| SCHEMBL29355998 | 0.77 | CDC25A (0.62) | ALDH1A1KMT2ACDC25ACDC25BMAPT | |
| SCHEMBL4208096 | 0.76 | SMN1; SMN2 (0.66) | ALDH1A1KMT2ACDC25ACDC25BMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | ALDH1A1 720/4885KMT2A 2263/4885CDC25A 4123/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.