Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.55 |
| ▸ | METAP2 | P50579 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27809488 | 0.84 | TP53 (0.77) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL21123650 | 0.82 | TP53 (0.78) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL6404136 | 0.82 | KMT2A (0.64) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL18292561 | 0.82 | MAPT (0.66) | ALDH1A1POLBLMNAL3MBTL1RXFP1 | |
| SCHEMBL29381993 | 0.82 | SMN1; SMN2 (0.65) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL6404317 | 0.81 | ALDH1A1 (0.64) | ALDH1A1KDM4EKMT2APOLBSMN1; SMN2 | |
| SCHEMBL6402656 | 0.81 | ALDH1A1 (0.72) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL29453959 | 0.79 | ALDH1A1 (0.71) | ALDH1A1KDM4EMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15983434 | 0.77 | ALDH1A1 (0.77) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL14426679 | 0.76 | SMN1; SMN2 (0.92) | ALDH1A1MEN1KMT2ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101805302-B | 2- (4-phenyl-3-aryloxy-1, 2, 4-triazole-5-sulfenyl) acetamide and synthesis and application thereof | UNIV NORTHWEST NORMAL | 2012-05-09 | — | — | CN | disclosed |
| CN-101805302-A | 2-(4-phenyl-3-aryloxy-1,2,4-triazole-5-sulfenyl) acetamide and synthesis and application thereof | UNIV NORTHWEST NORMAL | 2010-08-18 | — | — | CN | disclosed |