Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | NT5E | P21589 | 1/20 | 0.43 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | ACR | P10323 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6716602 | 0.96 | POLB (0.53) | POLBMAPTPKMTSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10337518 | 0.94 | POLB (0.52) | POLBMAPTPKMTSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6404909 | 0.92 | POLB (0.50) | POLBMAPTPKMTSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6404908 | 0.84 | POLB (0.46) | POLBMAPTPKMTSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL7558793 | 0.84 | POLB (0.47) | POLBMAPTPKMTSHRSMN1; SMN2 | |
| SCHEMBL3161812 | 0.82 | MAPT (0.74) | POLBMAPTPKMTSHRSMN1; SMN2 | |
| SCHEMBL8959035 | 0.82 | POLB (0.47) | POLBMAPTPKMTSHRSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL10701280 | 0.81 | POLB (0.45) | POLBMAPTPKMTSHRSMN1; SMN2 | |
| SCHEMBL6203459 | 0.81 | POLB (0.50) | POLBMAPTPKMTSHRSMN1; SMN2 | |
| SCHEMBL16027098 | 0.81 | PKM (0.73) | POLBMAPTPKMTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105473700-B | Bleaching and oxidation catalyst | 切姆森蒂有限公司 | 2021-11-02 | — | — | CN | disclosed |
| EP-3033409-B1 | COMPOSITION | CATEXEL TECH LIMITED (GB) | 2021-09-22 | — | — | EP | disclosed |
| EP-3011004-B2 | BLEACH AND OXIDATION CATALYST | CATEXEL TECH LIMITED (GB) | 2020-07-01 | — | — | EP | disclosed |
| US-10370621-B2 | Bleaching formulations comprising particles and transition metal ion-containing bleaching catalysts | CHEMSENTI LIMITED (GB) | 2019-08-06 | — | — | US | disclosed |
| EP-3011004-B1 | BLEACH AND OXIDATION CATALYST | CHEMSENTI LTD (GB) | 2017-07-26 | — | — | EP | disclosed |
| EP-3033409-A1 | COMPOSITION | Chemsenti Limited (GB) | 2016-06-22 | — | — | EP | disclosed |
| US-20160160160-A1 | COMPOSITION | CHEMSENTI LIMITED (GB) | 2016-06-09 | — | — | US | disclosed |
| EP-3011004-A1 | BLEACH AND OXIDATION CATALYST | Chemsenti Limited (GB) | 2016-04-27 | — | — | EP | disclosed |
| US-20160102276-A1 | BLEACH AND OXIDATION CATALYST | CHEMSENTI LIMITED (GB) | 2016-04-14 | — | — | US | disclosed |
| WO-2015022502-A1 | COMPOSITION | CHEMSENTI LIMITED (GB) | 2015-02-19 | — | — | WO | disclosed |
| WO-2014202954-A1 | BLEACH AND OXIDATION CATALYST | CHEMSENTI LIMITED (GB) | 2014-12-24 | — | — | WO | disclosed |
| US-20050267005-A1 | Multicompartment water-soluble pouch, each compartment of which is a different color and contains different components, one of which contains is a mineral oil liquid matrix and a source of peracid; consumers need not contact detergent ingredients | THE PROCTER & GAMBLE COMPANY (US) | 2005-12-01 | — | — | US | disclosed |
| EP-0284132-B1 | Quaternary ammonium or phosphonium peroxy carbonic acid precursors and their use in detergent bleach compositions | UNILEVER NV (NL) | 1994-01-12 | — | — | EP | disclosed |
| US-4988817-A | Reacting a cationic hydroxyl containing compound with phosgene in an aprotic solvent, followed by reaction with alcohol or a compound with a removeable hydrogen group | LEVER BROTHERS COMPANY, DIVISION OF CONOPCO, INC. (US) | 1991-01-29 | — | — | US | disclosed |
| EP-0284132-A2 | Quaternary ammonium or phosphonium peroxy carbonic acid precursors and their use in detergent bleach compositions | UNILEVER N.V. (NL) | 1988-09-28 | — | — | EP | disclosed |