SCHEMBL6404980

SCHEMBL6404980

Clc1cccc(-c2nnc(SCc3ccccc3)[nH]2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.52
CTSB P07858 2/20 0.51
TOP2A P11388 1/20 0.51
KMT2A Q03164 5/20 0.48
MEN1 O00255 4/20 0.48
MAOB P27338 1/20 0.48
POLB P06746 1/20 0.47
ALDH1A1 P00352 3/20 0.47
CXCR2 P25025 1/20 0.45
LMNA P02545 2/20 0.44
USP2 O75604 1/20 0.44
HRH1 P35367 1/20 0.44
DAO P14920 2/20 0.43
RAB9A P51151 1/20 0.43
SCN2A Q99250 1/20 0.43
HTT P42858 2/20 0.42
GAA P10253 1/20 0.42
HPGD P15428 1/20 0.42
PIN1 Q13526 1/20 0.41
ATM Q13315 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6407005 0.87 ACMSD (0.45) L3MBTL1CTSBTOP2AKMT2AMEN1
SCHEMBL6015583 0.82 CYP1A2 (0.45) L3MBTL1KMT2AMEN1ALDH1A1LMNA
SCHEMBL6405550 0.78 MAOB (0.54) L3MBTL1CTSBTOP2AKMT2AMEN1
SCHEMBL6408132 0.75 HRH1 (0.41) ALDH1A1HRH1DAORAB9ASCN2A
SCHEMBL14027551 0.73 EGFR (0.54) L3MBTL1KMT2APOLBALDH1A1DAO
SCHEMBL6409235 0.72 NPY5R (0.43) L3MBTL1KMT2AMEN1POLBHRH1
SCHEMBL6403939 0.72 VCP (0.50) L3MBTL1KMT2AMEN1POLBALDH1A1
SCHEMBL14028294 0.70 HPGD (0.60) KMT2ALMNARAB9AHTTHPGD
SCHEMBL16157094 0.70 EGFR (0.74) L3MBTL1POLBALDH1A1RAB9AHTT
SCHEMBL3825940 0.70 HRH1 (0.56) MAOBALDH1A1HRH1RAB9ASCN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050288347-A1 Certain triazole-based compounds, compositions, and uses thereof AGRIUS GROUP, LLC. 2005-12-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050288347-A1 Certain triazole-based compounds, compositions, and uses thereof ABCG2, ATP5ME, DNTT L3MBTL1 2749/4885CTSB 872/4885TOP2A 698/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.