Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.78 |
| ▸ | TP53 | P04637 | 1/20 | 0.78 |
| ▸ | LMNA | P02545 | 5/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALPG | P10696 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6405883 | 0.89 | GAA (1.00) | GAAALDH1A1TP53LMNARAB9A | |
| SCHEMBL6407529 | 0.85 | GAA (0.71) | GAAALDH1A1TP53LMNARAB9A | |
| SCHEMBL4199249 | 0.82 | ALDH1A1 (0.58) | GAAALDH1A1TP53LMNARAB9A | |
| SCHEMBL4210772 | 0.80 | LMNA (0.84) | GAAALDH1A1TP53LMNARAB9A | |
| SCHEMBL18559316 | 0.80 | LMNA (1.00) | GAAALDH1A1TP53LMNARAB9A | |
| SCHEMBL4216784 | 0.79 | HDAC2 (0.61) | GAAALDH1A1TP53LMNARAB9A | |
| SCHEMBL4200193 | 0.78 | LMNA (0.84) | GAAALDH1A1TP53LMNARAB9A | |
| SCHEMBL4198392 | 0.78 | LMNA (0.84) | GAAALDH1A1TP53LMNARAB9A | |
| SCHEMBL15731825 | 0.78 | LMNA (0.58) | GAAALDH1A1TP53LMNARAB9A | |
| SCHEMBL4203779 | 0.78 | LMNA (0.82) | GAAALDH1A1TP53LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | GAA 85/4885ALDH1A1 720/4885TP53 1524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.