Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 5/20 | 0.43 |
| ▸ | RPS6KA5 | O75582 | 2/20 | 0.43 |
| ▸ | RPS6KA4 | O75676 | 2/20 | 0.43 |
| ▸ | PRKACA | P17612 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | PRKX | P51817 | 2/20 | 0.43 |
| ▸ | PRKG1 | Q13976 | 2/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.43 |
| ▸ | GSK3A | P49840 | 1/20 | 0.43 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.43 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.43 |
| ▸ | SGK2 | Q9HBY8 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6412108 | 0.85 | FPR3 (0.46) | MMEMAPK1CYP3A4PIN1ALDH1A1 | |
| SCHEMBL1153618 | 0.80 | MAPK1 (0.57) | MMEMAPK1CYP3A4ROCK2ROCK1 | |
| SCHEMBL4965651 | 0.80 | ECE1 (0.47) | KMT2AACELMNA | |
| SCHEMBL1152879 | 0.78 | MME (0.61) | MMEMAPK1CYP3A4ROCK2ROCK1 | |
| SCHEMBL1152668 | 0.78 | MME (0.58) | MMEMAPK1CYP3A4ROCK2ROCK1 | |
| SCHEMBL1153080 | 0.77 | MME (0.60) | MMEMAPK1CYP3A4ROCK2ROCK1 | |
| SCHEMBL4965656 | 0.76 | ACACB (0.50) | NPC1RAB9AKMT2ALMNAALDH1A1 | |
| SCHEMBL4962899 | 0.76 | HPGD (0.38) | MMECYP3A4KMT2ALMNACYP2C9 | |
| SCHEMBL4962001 | 0.75 | SMN1; SMN2 (0.53) | MAPK1CYP3A4NPC1RAB9AKMT2A | |
| SCHEMBL3897966 | 0.73 | MAPK1 (0.68) | MMEMAPK1CYP3A4ROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288338-A1 | Amido compounds and their use as pharmaceuticals | INCYTE CORPORATION | 2005-12-29 | — | — | US | claimed |
| US-20050288338-A1 | Amido compounds and their use as pharmaceuticals | INCYTE CORPORATION | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288338-A1 | Amido compounds and their use as pharmaceuticals | HSD11B1, CYP11B1, HSD11B2 | MME 342/4885MAPK1 829/4885CYP3A4 566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.