Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | JAK2 | O60674 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.49 |
| ▸ | KLK1 | P06870 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
| ▸ | PRKCA | P17252 | 1/20 | 0.47 |
| ▸ | GRK2 | P25098 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20810071 | 0.86 | SMN1; SMN2 (0.59) | ALDH1A1POLBSMN1; SMN2HTTJAK2 | |
| SCHEMBL6403827 | 0.82 | POLB (0.65) | ALDH1A1POLBSMN1; SMN2HTTJAK2 | |
| SCHEMBL20810279 | 0.82 | POLB (0.53) | ALDH1A1POLBSMN1; SMN2HTTJAK2 | |
| SCHEMBL6405173 | 0.82 | HPGD (0.57) | ALDH1A1POLBSMN1; SMN2HTTL3MBTL1 | |
| SCHEMBL6401623 | 0.81 | NOTUM (0.61) | ALDH1A1POLBSMN1; SMN2HTTJAK2 | |
| SCHEMBL6402261 | 0.81 | HPGD (0.53) | ALDH1A1POLBSMN1; SMN2LMNACYP1A2 | |
| SCHEMBL6402512 | 0.81 | ROCK2 (0.59) | ALDH1A1POLBSMN1; SMN2HTTJAK2 | |
| SCHEMBL6410100 | 0.81 | HTT (0.57) | ALDH1A1POLBSMN1; SMN2HTTJAK2 | |
| SCHEMBL6404369 | 0.80 | SMN1; SMN2 (0.56) | ALDH1A1POLBSMN1; SMN2HTTJAK2 | |
| SCHEMBL6404124 | 0.80 | POLB (0.69) | ALDH1A1POLBSMN1; SMN2HTTJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | ALDH1A1 1486/4885POLB 3713/4885SMN1; SMN2 4458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.