Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | CSGALNACT1 | Q8TDX6 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6408055 | 0.84 | HTT (0.54) | SMN1; SMN2POLBALDH1A1CYP1A2HTT | |
| SCHEMBL6408040 | 0.83 | POLB (0.62) | NPC1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL6409325 | 0.83 | NPC1 (0.64) | NPC1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL6405148 | 0.81 | NAMPT (0.53) | NPC1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL6405193 | 0.81 | MAPT (0.62) | NPC1SMN1; SMN2RAB9ATP53MEN1 | |
| SCHEMBL6403360 | 0.81 | SIRT2 (0.55) | NPC1SMN1; SMN2RAB9AALDH1A1CYP1A2 | |
| SCHEMBL6403149 | 0.81 | NPC1 (0.57) | NPC1SMN1; SMN2RAB9AMEN1KMT2A | |
| SCHEMBL6401623 | 0.79 | NOTUM (0.61) | NPC1SMN1; SMN2RAB9AKMT2AHPGD | |
| SCHEMBL6407970 | 0.79 | POLB (0.59) | NPC1SMN1; SMN2RAB9ATP53MEN1 | |
| SCHEMBL6402452 | 0.78 | POLB (0.56) | NPC1SMN1; SMN2RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | NPC1 1915/4885SMN1; SMN2 4458/4885RAB9A 4044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.