Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | FLT4 | P35916 | 1/20 | 0.50 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | PRKCA | P17252 | 1/20 | 0.49 |
| ▸ | GRK2 | P25098 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6408055 | 0.87 | HTT (0.54) | L3MBTL1SMN1; SMN2ROCK2PRKCAGRK2 | |
| SCHEMBL6405193 | 0.82 | MAPT (0.62) | L3MBTL1CYP2C19SMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL3606928 | 0.82 | CYP2C9 (0.62) | L3MBTL1CYP2C9CYP2C19SMN1; SMN2CYP2E1 | |
| SCHEMBL6405937 | 0.81 | NPC1 (0.56) | L3MBTL1SMN1; SMN2ALDH1A1RAB9AKDM4E | |
| SCHEMBL20791734 | 0.81 | ROCK2 (0.59) | CYP2C9CYP2C19SMN1; SMN2CYP2E1CYP2A6 | |
| SCHEMBL6408040 | 0.81 | POLB (0.62) | L3MBTL1CYP2C9CYP2C19SMN1; SMN2ALDH1A1 | |
| SCHEMBL5658056 | 0.80 | TRPV1 (0.58) | — | |
| SCHEMBL6405148 | 0.80 | NAMPT (0.53) | L3MBTL1CYP2C9SMN1; SMN2ALDH1A1NAMPT | |
| SCHEMBL6402683 | 0.79 | NTRK1 (0.48) | L3MBTL1SMN1; SMN2ALDH1A1RAB9ANPC1 | |
| SCHEMBL6401623 | 0.77 | NOTUM (0.61) | L3MBTL1CYP2C19SMN1; SMN2ROCK2PRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | SIRT2 973/4885L3MBTL1 607/4885CYP2C9 188/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.