Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6404847 | 0.90 | ALDH1A1 (0.59) | ALDH1A1RAB9AGFERHPGDPOLB | |
| SCHEMBL5376856 | 0.82 | ALDH1A1 (0.52) | ALDH1A1RAB9AGFERHPGDPOLB | |
| SCHEMBL6406023 | 0.78 | NPC1 (0.47) | ALDH1A1RAB9AHPGDPOLBTSHR | |
| SCHEMBL6403939 | 0.76 | VCP (0.50) | ALDH1A1RAB9AHPGDPOLBKMT2A | |
| SCHEMBL5376644 | 0.75 | ALDH1A1 (0.56) | ALDH1A1RAB9AGFERHPGDPOLB | |
| SCHEMBL5371958 | 0.75 | ALDH1A1 (0.56) | ALDH1A1RAB9AGFERHPGDPOLB | |
| SCHEMBL5378895 | 0.74 | ALDH1A1 (0.54) | ALDH1A1RAB9AGFERHPGDPOLB | |
| SCHEMBL6405045 | 0.73 | GRK6 (0.60) | ALDH1A1RAB9AHPGDKMT2AHSD17B10 | |
| SCHEMBL16171163 | 0.73 | GRK6 (0.48) | ALDH1A1RAB9APOLBKMT2AMEN1 | |
| SCHEMBL14907889 | 0.72 | POLB (0.52) | ALDH1A1HPGDPOLBKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | ALDH1A1 720/4885RAB9A 4278/4885GFER 932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.