Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6405896 | 0.84 | SMN1; SMN2 (0.69) | ALDH1A1CYP1A2CYP3A4SMN1; SMN2LMNA | |
| SCHEMBL6402396 | 0.83 | SMN1; SMN2 (0.77) | ALDH1A1CYP1A2CYP3A4SMN1; SMN2LMNA | |
| SCHEMBL6402577 | 0.82 | SMN1; SMN2 (0.72) | ALDH1A1CYP1A2CYP3A4SMN1; SMN2LMNA | |
| SCHEMBL6403049 | 0.82 | MAPT (0.52) | ALDH1A1SMN1; SMN2POLBNPC1RAB9A | |
| SCHEMBL6408047 | 0.82 | SMN1; SMN2 (0.56) | ALDH1A1CYP1A2SMN1; SMN2LMNAPOLB | |
| SCHEMBL13902168 | 0.81 | CYP1A2 (0.66) | ALDH1A1CYP1A2CYP2C19CYP3A4SMN1; SMN2 | |
| SCHEMBL20810186 | 0.80 | CTSA (0.49) | ALDH1A1CYP1A2CYP2C19CYP3A4SMN1; SMN2 | |
| SCHEMBL20810036 | 0.80 | CYP1A2 (0.51) | ALDH1A1CYP1A2CYP2C19CYP3A4SMN1; SMN2 | |
| SCHEMBL6402991 | 0.79 | MAPT (0.56) | ALDH1A1CYP1A2SMN1; SMN2LMNAPOLB | |
| SCHEMBL6407606 | 0.79 | SMN1; SMN2 (0.71) | ALDH1A1CYP1A2CYP3A4SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | ALDH1A1 1486/4885CYP1A2 3/4885CYP2C19 295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.