Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6402463 | 0.86 | KMT2A (0.48) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL6408049 | 0.86 | NPC1 (0.55) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL6408618 | 0.85 | SMN1; SMN2 (0.62) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL6402547 | 0.83 | SMN1; SMN2 (0.57) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL6410111 | 0.83 | SMN1; SMN2 (0.62) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL6405915 | 0.82 | NPC1 (0.64) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL6405972 | 0.82 | ALDH1A1 (0.65) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL6405237 | 0.82 | RAB9A (0.65) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL6402530 | 0.81 | KMT2A (0.54) | SMN1; SMN2ALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL6407778 | 0.81 | HSD17B10 (0.62) | MAPTSMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | MAPT 4543/4885SMN1; SMN2 4458/4885ALDH1A1 1486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.