Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.42 |
| ▸ | GRK6 | P43250 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | STAT6 | P42226 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6408132 | 0.82 | HRH1 (0.41) | HRH1SCN2AALDH1A1GAAPIN1 | |
| SCHEMBL21763890 | 0.80 | MAPK14 (0.53) | HRH1HRH4SCN2AGRK6ALDH1A1 | |
| SCHEMBL14907729 | 0.79 | GRK6 (0.63) | HRH1HRH4SCN2AGRK6ALDH1A1 | |
| SCHEMBL18540506 | 0.78 | GRK6 (0.50) | HRH1HRH4SCN2AGRK6ALDH1A1 | |
| SCHEMBL6404359 | 0.76 | HRH1 (0.49) | HRH1HRH4SCN2AGRK6PIN1 | |
| SCHEMBL6410250 | 0.76 | HRH1 (0.46) | HRH1HRH4SCN2AGRK6ALDH1A1 | |
| SCHEMBL6411295 | 0.76 | MAPK14 (0.41) | ALDH1A1KDM4ENPC1CYP1A2CYP3A4 | |
| SCHEMBL6406678 | 0.74 | MAPK14 (0.47) | HRH1HRH4SCN2AGRK6ALDH1A1 | |
| SCHEMBL6407620 | 0.72 | ALDH1A1 (0.48) | HRH1HRH4GRK6ALDH1A1GAA | |
| SCHEMBL6408996 | 0.71 | MAPK14 (0.39) | ALDH1A1ATMKDM4ENPC1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | HRH1 2884/4885HRH4 2750/4885SCN2A 4359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.