Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.45 |
| ▸ | XPO1 | O14980 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GRK6 | P43250 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6410250 | 0.80 | HRH1 (0.46) | ALDH1A1SMN1; SMN2GAAHPGDKDM4E | |
| SCHEMBL21763890 | 0.80 | MAPK14 (0.53) | ALDH1A1L3MBTL1SMN1; SMN2GAAHPGD | |
| SCHEMBL18540506 | 0.79 | GRK6 (0.50) | ALDH1A1L3MBTL1POLBSMN1; SMN2GAA | |
| SCHEMBL6404690 | 0.79 | CYP1A2 (0.53) | ALDH1A1L3MBTL1MAPK1POLBSMN1; SMN2 | |
| SCHEMBL14907729 | 0.78 | GRK6 (0.63) | ALDH1A1POLBSMN1; SMN2KDM4EGRIN1 | |
| SCHEMBL6404359 | 0.76 | HRH1 (0.49) | MAPK1POLBPIN1KMT2AMEN1 | |
| SCHEMBL14907872 | 0.72 | MAPT (0.57) | L3MBTL1MAPK1GAAHPGDKDM4E | |
| SCHEMBL6405975 | 0.72 | HRH1 (0.44) | ALDH1A1SMN1; SMN2GAAHPGDKDM4E | |
| SCHEMBL16171055 | 0.72 | GRK6 (0.52) | ALDH1A1KDM4EPIN1KMT2AMAPT | |
| SCHEMBL11233673 | 0.69 | L3MBTL1 (0.46) | ALDH1A1L3MBTL1MAPK1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | ALDH1A1 720/4885L3MBTL1 2749/4885MAPK1 4613/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.