Furfural

Furfural

SCHEMBL6406316

C[N+](=O)[O-].O=Cc1ccco1

nearest known ligand 0.72

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.72
RAB9A P51151 1/20 0.42
HSP90AA1 P07900 1/20 0.42
G6PD P11413 1/20 0.42
POLB P06746 6/20 0.42
MEN1 O00255 2/20 0.42
KMT2A Q03164 2/20 0.42
HCAR2 Q8TDS4 1/20 0.40
TLR9 Q9NR96 1/20 0.39
MAPT P10636 4/20 0.39
HTT P42858 3/20 0.39
L3MBTL1 Q9Y468 3/20 0.39
PKM P14618 2/20 0.39
ERN1 O75460 1/20 0.38
GSK3B P49841 2/20 0.38
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
KDM4E B2RXH2 1/20 0.38
APEX1 P27695 1/20 0.38
RECQL P46063 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Furfural SCHEMBL10811266 0.85 ALDH1A1 (1.00) ALDH1A1RAB9APOLBMEN1KMT2A
Furfural SCHEMBL626705 0.85 ALDH1A1 (1.00) ALDH1A1RAB9APOLBMEN1KMT2A
Furfural SCHEMBL20439 0.85
Furfural SCHEMBL27424419 0.85 ALDH1A1 (0.67) ALDH1A1RAB9AHSP90AA1G6PDPOLB
Furfural SCHEMBL5595778 0.83 ALDH1A1 (0.86) ALDH1A1RAB9APOLBMEN1KMT2A
Furfural SCHEMBL3322709 0.83
Furfural SCHEMBL11537859 0.83
Furfural SCHEMBL896786 0.83 ALDH1A1 (0.95) ALDH1A1RAB9APOLBMEN1KMT2A
Furfural SCHEMBL11763411 0.83
Furfural SCHEMBL2197116 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050043551-A1 Method of obtaining 2-(2-nitrovinyl)-furan and the use thereof as a coccidiostatic CENTRO DE BIOACTIVOS QUIMICOS (CU) 2005-02-24 US claimed
EP-1439172-A1 METHOD OF OBTAINING 2-(2-NITROVINYL)-FURAN AND THE USE THEREOF AS A COCCIDIOSTATIC Centro De Bioactivos Quimicos (CBQ) (CU) 2004-07-21 EP claimed