Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 6/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6404449 | 0.91 | GAA (0.54) | ALDH1A1TSHRGAALMNAUSP2 | |
| SCHEMBL4649550 | 0.90 | ALDH1A1 (0.41) | ALDH1A1TSHRGAALMNAUSP2 | |
| SCHEMBL6409604 | 0.90 | ALDH1A1 (0.49) | ALDH1A1TSHRGAALMNAUSP2 | |
| SCHEMBL6403396 | 0.88 | GAA (0.44) | ALDH1A1TSHRGAALMNAUSP2 | |
| SCHEMBL4649545 | 0.88 | GAA (0.38) | ALDH1A1TSHRGAALMNAUSP2 | |
| SCHEMBL4648983 | 0.84 | ALDH1A1 (0.53) | ALDH1A1TSHRGAALMNAUSP2 | |
| SCHEMBL6409849 | 0.82 | GAA (0.52) | ALDH1A1TSHRGAALMNAUSP2 | |
| SCHEMBL4686505 | 0.82 | GAA (0.53) | ALDH1A1TSHRGAALMNAUSP2 | |
| SCHEMBL6404869 | 0.81 | GAA (0.56) | ALDH1A1TSHRGAALMNAHTT | |
| SCHEMBL6406182 | 0.80 | GAA (0.49) | ALDH1A1TSHRGAALMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050282838-A1 | Compounds, compositions, and methods | CYTOKINETICS, INC. | 2005-12-22 | — | — | US | claimed |
| US-20050282838-A1 | Compounds, compositions, and methods | CYTOKINETICS, INC. | 2005-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050282838-A1 | Compounds, compositions, and methods | PCNA, MKI67, TP53 | ALDH1A1 1008/4885TSHR 4678/4885GAA 349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.