Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | OXTR | P30559 | 2/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6251016 | 0.80 | ALDH1A1 (0.67) | KMT2AMEN1ALDH1A1TSHRNPSR1 | |
| Hydrochloric Acid SCHEMBL11375354 | 0.76 | TLR8 (0.57) | KMT2AMEN1ALDH1A1TSHRTLR8 | |
| SCHEMBL11919912 | 0.76 | TNKS2 (0.58) | KMT2AMEN1ALDH1A1TSHRTLR8 | |
| Hydrochloric Acid SCHEMBL11154758 | 0.75 | POLB (0.53) | KMT2AMEN1ALDH1A1TSHRTLR8 | |
| SCHEMBL6244967 | 0.74 | KMT2A (0.63) | KMT2AMEN1ALDH1A1TSHRHPGD | |
| SCHEMBL14925000 | 0.73 | TLR8 (0.46) | KMT2AMEN1ALDH1A1TSHRTLR8 | |
| SCHEMBL5006533 | 0.72 | TLR8 (0.45) | KMT2AMEN1ALDH1A1TSHRTLR8 | |
| SCHEMBL5002770 | 0.72 | HSP90AA1 (0.60) | KMT2AMEN1ALDH1A1TSHRTLR8 | |
| SCHEMBL28255661 | 0.71 | TP53 (0.51) | KMT2AMEN1ALDH1A1TSHRNPSR1 | |
| SCHEMBL6406560 | 0.71 | ALDH1A1 (0.62) | KMT2AMEN1ALDH1A1TLR8NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | KMT2A 2263/4885MEN1 3562/4885ALDH1A1 720/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.