Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | TSHR | P16473 | 4/20 | 0.67 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 5/20 | 0.65 |
| ▸ | OXTR | P30559 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.61 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | USP2 | O75604 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ALPG | P10696 | 1/20 | 0.55 |
| ▸ | CDC25A | P30304 | 1/20 | 0.55 |
| ▸ | CDC25B | P30305 | 1/20 | 0.55 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.55 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6248366 | 0.87 | HPGD (0.63) | ALDH1A1TSHRMEN1KMT2AHPGD | |
| SCHEMBL11919912 | 0.84 | TNKS2 (0.58) | ALDH1A1TSHRMEN1KMT2AOXTR | |
| SCHEMBL6404885 | 0.83 | TSHR (0.72) | ALDH1A1TSHRMEN1KMT2AHPGD | |
| SCHEMBL6246142 | 0.82 | ALDH1A1 (0.71) | ALDH1A1TSHRMEN1KMT2AHPGD | |
| SCHEMBL10627154 | 0.82 | OXTR (0.88) | ALDH1A1TSHRMEN1KMT2AHPGD | |
| SCHEMBL6405572 | 0.82 | HPGD (0.73) | ALDH1A1TSHRMEN1KMT2AHPGD | |
| SCHEMBL6406205 | 0.81 | MEN1 (0.71) | ALDH1A1TSHRMEN1KMT2AHPGD | |
| SCHEMBL6407799 | 0.80 | ALDH1A1 (0.74) | ALDH1A1MEN1KMT2AHPGDNPSR1 | |
| SCHEMBL6406937 | 0.80 | KMT2A (0.54) | ALDH1A1TSHRMEN1KMT2AHPGD | |
| SCHEMBL1104405 | 0.79 | OXTR (0.65) | ALDH1A1TSHRMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005044008-A2 | 2 -AMINOTHIOPHENE COMPOUNDS AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2005-05-19 | — | — | WO | disclosed |