SCHEMBL6406953

SCHEMBL6406953

CCCCCC1CCC(C2CCC(CCC(F)(F)Oc3cc(F)c(F)c(F)c3)CC2)CC1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6406948 1.00 GAA (0.30) GAAMAPT
SCHEMBL6406955 1.00 GAA (0.30) GAAMAPT
SCHEMBL12976729 0.85
SCHEMBL12624286 0.85
SCHEMBL7524273 0.85
SCHEMBL7524284 0.85
SCHEMBL7524289 0.85
SCHEMBL18568872 0.84
SCHEMBL19775394 0.83
SCHEMBL12622608 0.82

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6864397-B2 Difluoromethyl ether derivative and process for producing the same CHISSO CORPORATION (JP) 2005-03-08 US disclosed
US-6827876-B2 Using alpha, alpha -difluorocyclohexylidene derivative as starting material to obtain difluoromethyl ether derivative CHISSO CORPORATION (JP) 2004-12-07 US disclosed
US-20040016906-A1 Difluoromethyl ether derivative and process for producing the same JNC CORPORATION (JP) 2004-01-29 US disclosed
US-20040004207-A1 Difluoromethyl ether derivative and process for producing the same JNC CORPORATION (JP) 2004-01-08 US disclosed
US-6605747-B2 Reacting the starting material, an alpha , alpha -difluorocyclohexylidene derivative with a halogen to produce an intermediate, reacting the intermediate with a phenol compound in presence of a base CHISSO CORPORATION (JP) 2003-08-12 US disclosed
US-20020120168-A1 Difluoromethyl ether derivative and process for producing the same JNC PETROCHEMICAL CORPORATION (JP) 2002-08-29 US disclosed
EP-1182186-A2 Difluoromethyl ether derivative and process for producing the same CHISSO CORPORATION (JP) 2002-02-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040004207-A1 Difluoromethyl ether derivative and process for producing the same RCC1, PYM1, SCFD1 GAA 4444/4885MAPT 4568/4885
US-20040016906-A1 Difluoromethyl ether derivative and process for producing the same RCC1, SCFD1, AFF1 GAA 4455/4885MAPT 4563/4885
US-20020120168-A1 Difluoromethyl ether derivative and process for producing the same LEF1, AFF1, RCC1 GAA 4301/4885MAPT 4284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.