Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Heptane SCHEMBL652606 | 0.97 | TSHR (0.57) | TSHRTHRBSPHK1LMNAALDH1A1 | |
| Isopropyl Alcohol SCHEMBL28547099 | 0.93 | TSHR (0.61) | TSHRTHRBSPHK1LMNAALDH1A1 | |
| Hexane SCHEMBL7785141 | 0.93 | TSHR (0.50) | TSHRTHRBSPHK1LMNAALDH1A1 | |
| Heptane SCHEMBL29253938 | 0.93 | TSHR (0.61) | TSHRTHRBSPHK1LMNAALDH1A1 | |
| Heptane SCHEMBL6217 | 0.93 | TSHR (0.61) | TSHRTHRBSPHK1LMNAALDH1A1 | |
| Dodecane SCHEMBL15048503 | 0.93 | TSHR (0.61) | TSHRTHRBSPHK1LMNAALDH1A1 | |
| Decane SCHEMBL11321882 | 0.93 | TSHR (0.61) | TSHRTHRBSPHK1LMNAALDH1A1 | |
| Hexane SCHEMBL2687900 | 0.93 | TSHR (0.50) | TSHRTHRBSPHK1LMNAALDH1A1 | |
| Heptane SCHEMBL9263200 | 0.93 | TSHR (0.61) | TSHRTHRBSPHK1LMNAALDH1A1 | |
| Octane SCHEMBL28183932 | 0.93 | TSHR (0.61) | TSHRTHRBSPHK1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050222098-A1 | Regulation of meiosis | NOVO NORDISK A/S (DK) | 2005-10-06 | — | — | US | disclosed |
| EP-0767798-B1 | STEROL DERIVATIVES USED FOR REGULATION OF MEIOSIS | NOVO NORDISK AS (DK) | 2003-09-03 | — | — | EP | disclosed |
| US-20030004148-A1 | Regulation of meiosis | NOVO NORDISK A/S (DK) | 2003-01-02 | — | — | US | disclosed |
| US-5716777-A | REGULATING MEIOSIS IN MAMMALIAN GERM CELL BY ADMINISTERING SPECIFIED STEROL IN VITRO | NOVO NORDISK A/S (DK) | 1998-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222098-A1 | Regulation of meiosis | ALPG, MNS1, BUB1B | TSHR 4376/4885THRB 3107/4885SPHK1 2469/4885 |
| US-20030004148-A1 | Regulation of meiosis | ALPG, MNS1, BUB1B | TSHR 4376/4885THRB 3107/4885SPHK1 2469/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.