Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 7/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.52 |
| ▸ | CYP2E1 | P05181 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.52 |
| ▸ | CYP2C8 | P10632 | 5/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.52 |
| ▸ | CYP2B6 | P20813 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | PTGES | O14684 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6405965 | 0.83 | KDM4E (0.47) | CYP2C9CYP2C19CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL17068769 | 0.80 | MAPT (0.41) | CYP2C9CYP2C19CYP1A2CYP2E1CYP2C8 | |
| SCHEMBL17068802 | 0.80 | ALDH1A1 (0.51) | CYP2C9CYP2C19CYP1A2CYP2E1CYP2C8 | |
| SCHEMBL6404879 | 0.78 | ALDH1A1 (0.54) | NPC1RAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL6405244 | 0.77 | LMNA (0.45) | CYP2C9CYP2C19CYP1A2NPC1RAB9A | |
| SCHEMBL6403883 | 0.77 | POLB (0.44) | MAPTALDH1A1TSHRHTT | |
| SCHEMBL21763932 | 0.77 | TDP1 (0.46) | CYP1A2MAPTALDH1A1TSHR | |
| SCHEMBL6408541 | 0.77 | KDM4E (0.43) | CYP2C9CYP2C19CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL6405373 | 0.76 | GSK3A (0.50) | CYP2C9CYP2C19CYP2E1CYP3A4CYP2C8 | |
| SCHEMBL23527296 | 0.75 | AR (0.52) | CYP2C9CYP2C19CYP1A2CYP3A4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2005-12-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050288347-A1 | Certain triazole-based compounds, compositions, and uses thereof | ABCG2, ATP5ME, DNTT | CYP2C9 128/4885CYP2C19 142/4885CYP1A2 93/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.