Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 9/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 8/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 8/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6407737 | 0.86 | HDAC6 (0.49) | NPC1HPGDHDAC1HDAC6MEN1 | |
| SCHEMBL6404311 | 0.85 | NPC1 (0.55) | NPC1TP53MAPTHPGDTSHR | |
| SCHEMBL6408033 | 0.84 | NPC1 (0.52) | NPC1TSHRRAB9AHDAC1HDAC6 | |
| SCHEMBL6407951 | 0.82 | HDAC4 (0.54) | NPC1TP53MAPTHPGDRAB9A | |
| SCHEMBL6404074 | 0.82 | SMN1; SMN2 (0.51) | NPC1TP53TSHRRAB9ACYP1A2 | |
| SCHEMBL6403548 | 0.81 | KDM4E (0.53) | NPC1HPGDTSHRMEN1KMT2A | |
| SCHEMBL6409368 | 0.81 | TDP1 (0.52) | NPC1TP53MAPTRAB9AMEN1 | |
| SCHEMBL6406614 | 0.81 | NAMPT (0.48) | NPC1TP53RAB9AMEN1KMT2A | |
| SCHEMBL6405202 | 0.81 | HSP90AA1 (0.47) | NPC1HPGDTSHRRAB9AMEN1 | |
| SCHEMBL6405551 | 0.81 | KMT2A (0.41) | NPC1RAB9ACYP1A2CYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | NPC1 1915/4885TP53 4011/4885MAPT 4543/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.