Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.46 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6407737 | 0.87 | HDAC6 (0.49) | KDM4EMEN1HPGDKMT2APOLB | |
| SCHEMBL6402390 | 0.87 | FABP4 (0.44) | KDM4EMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL6403554 | 0.86 | POLB (0.58) | MEN1HPGDKMT2APOLBCA1 | |
| SCHEMBL6406674 | 0.86 | HPGD (0.58) | TSHRMEN1HPGDKMT2APOLB | |
| SCHEMBL6404074 | 0.86 | SMN1; SMN2 (0.51) | TSHRMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL6407951 | 0.84 | HDAC4 (0.54) | MEN1HPGDKMT2APOLBNPC1 | |
| SCHEMBL6405160 | 0.82 | POLB (0.51) | KDM4ETSHRMEN1HPGDKMT2A | |
| SCHEMBL6408021 | 0.82 | BCHE (0.42) | KDM4EMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL6407596 | 0.81 | NPC1 (0.58) | TSHRMEN1HPGDKMT2ANPC1 | |
| SCHEMBL6404399 | 0.81 | HSD17B10 (0.48) | KDM4EKMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | KDM4E 3126/4885TSHR 705/4885MEN1 3154/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.