Phthalimide

Phthalimide

SCHEMBL6407632

Nc1ccc(N)cc1.O=C1NC(=O)c2ccccc21.O=C1NC(=O)c2ccccc21

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.75
CASP7 P55210 3/20 0.62
CASP3 P42574 2/20 0.62
CASP6 P55212 2/20 0.62
CASP8 Q14790 2/20 0.62
CASP2 P42575 1/20 0.62
PARP1 P09874 3/20 0.48
POLB P06746 3/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
MAPT P10636 3/20 0.48
CYP3A4 P08684 2/20 0.48
TDP1 Q9NUW8 2/20 0.48
BLM P54132 2/20 0.48
NPSR1 Q6W5P4 2/20 0.48
RGS12 O14924 1/20 0.48
USP2 O75604 1/20 0.48
CYP1A2 P05177 1/20 0.48
THRB P10828 1/20 0.48
CYP2C9 P11712 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalimide SCHEMBL1616990 0.87 GSK3B (0.88) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL7771670 0.87 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL11040503 0.87 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL29366030 0.87 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL64 0.87 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL10192661 0.87 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL30125197 0.87 GSK3B (1.00) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL6407636 0.85 GSK3B (0.75) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL5742518 0.84 GSK3B (0.94) GSK3BCASP7CASP3CASP6CASP8
Phthalimide SCHEMBL1205294 0.84 GSK3B (0.94) GSK3BCASP7CASP3CASP6CASP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6919422-B2 Polyimide resin with reduced mold deposit GENERAL ELECTRIC COMPANY (US) 2005-07-19 US disclosed
US-20040260055-A1 Polyimide resin with reduced mold deposit GENERAL ELECTRIC COMPANY 2004-12-23 US disclosed