Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 7/20 | 0.60 |
| ▸ | RAB9A | P51151 | 7/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | TP53 | P04637 | 3/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6408618 | 0.96 | SMN1; SMN2 (0.62) | HSD17B10HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6402547 | 0.91 | SMN1; SMN2 (0.57) | HSD17B10HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6404235 | 0.90 | SMN1; SMN2 (0.56) | HSD17B10HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6408049 | 0.90 | NPC1 (0.55) | HSD17B10HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6402541 | 0.88 | RXFP1 (0.65) | HSD17B10HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6405888 | 0.88 | SMN1; SMN2 (0.53) | HSD17B10HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6410519 | 0.86 | NPC1 (0.59) | HSD17B10HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6405915 | 0.84 | NPC1 (0.64) | HSD17B10HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6407606 | 0.82 | SMN1; SMN2 (0.71) | HPGDNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6407762 | 0.82 | SMN1; SMN2 (0.71) | HPGDNPC1RAB9ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | SDS BIOTECH K.K. (JP) | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171358-A1 | Substituted isoxazole alkylamine derivative and agri-and horticultural fungicide | AHR, ERG28, CYP1A2 | HSD17B10 191/4885HPGD 3244/4885NPC1 1915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.